LHX1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LHX1_MOUSE
• UniProt AC: P63006
• Protein Name: LIM/homeobox protein Lhx1
• Gene Name: Lhx1
• Organism: Mus musculus (Mouse).
• Sequence Length: 406
• Subcellular Localization: Nucleus .
• Protein Description: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis..
• Protein Sequence: MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEGGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLDHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
129	Phosphorylation	SSVAKENSLHSATTG CCHHHCCCCCCCCCC	28.66	28066266
132	Phosphorylation	AKENSLHSATTGSDP HHCCCCCCCCCCCCC	32.38	28066266
134	Phosphorylation	ENSLHSATTGSDPSL CCCCCCCCCCCCCCC	34.40	28066266
135	Phosphorylation	NSLHSATTGSDPSLS CCCCCCCCCCCCCCC	34.11	28066266
137	Phosphorylation	LHSATTGSDPSLSPD CCCCCCCCCCCCCCC	44.23	28066266
140	Phosphorylation	ATTGSDPSLSPDSQD CCCCCCCCCCCCCCC	46.61	28066266
142	Phosphorylation	TGSDPSLSPDSQDPS CCCCCCCCCCCCCCC	30.88	28066266
145	Phosphorylation	DPSLSPDSQDPSQDD CCCCCCCCCCCCCCC	39.61	28066266
149	Phosphorylation	SPDSQDPSQDDAKDS CCCCCCCCCCCCCCH	55.31	28066266
156	Phosphorylation	SQDDAKDSESANVSD CCCCCCCHHCCCCCC	32.51	-
158	Phosphorylation	DDAKDSESANVSDKE CCCCCHHCCCCCCCC	29.15	-
162	Phosphorylation	DSESANVSDKEGGSN CHHCCCCCCCCCCCC	42.65	27841257
168	Phosphorylation	VSDKEGGSNENDDQN CCCCCCCCCCCCCCC	52.40	27841257

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LHX1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LHX1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LHX1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of LHX1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.