dbPTM

LHS1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LHS1_SCHPO
UniProt AC	Q10061
Protein Name	Heat shock protein 70 homolog lhs1
Gene Name	SPAC1F5.06
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	848
Subcellular Localization	Endoplasmic reticulum lumen .
Protein Description	Chaperone required for protein translocation and folding in the endoplasmic reticulum..
Protein Sequence	MKRSVLTIILFFSCQFWHAFASSVLAIDYGTEWTKAALIKPGIPLEIVLTKDTRRKEQSAVAFKGNERIFGVDASNLATRFPAHSIRNVKELLDTAGLESVLVQKYQSSYPAIQLVENEETTSGISFVISDEENYSLEEIIAMTMEHYISLAEEMAHEKITDLVLTVPPHFNELQRSILLEAARILNKHVLALIDDNVAVAIEYSLSRSFSTDPTYNIIYDSGSGSTSATVISFDTVEGSSLGKKQNITRIRALASGFTLKLSGNEINRKLIGFMKNSFYQKHGIDLSHNHRALARLEKEALRVKHILSANSEAIASIEELADGIDFRLKITRSVLESLCKDMEDAAVEPINKALKKANLTFSEINSIILFGGASRIPFIQSTLADYVSSDKISKNVNADEASVKGAAFYGASLTKSFRVKPLIVQDIINYPYLLSLGTSEYIVALPDSTPYGMQHNVTIHNVSTIGKHPSFPLSNNGELIGEFTLSNITDVEKVCACSNKNIQISFSSDRTKGILVPLSAIMTCEHGELSSKHKLGDRVKSLFGSHDESGLRNNESYPIGFTYKKYGEMSDNALRLASAKLERRLQIDKSKAAHDNALNELETLLYRAQAMVDDDEFLEFANPEETKILKNDSVESYDWLIEYGSQSPTSEVTDRYKKLDDTLKSISFRFDQAKQFNTSLENFKNALERAESLLTNFDVPDYPLNVYDEKDVKRVNSLRGTSYKKLGNQYYNDTQWLKDNLDSHLSHTLSEDPLIKVEELEEKAKRLQELTYEYLRRSLQQPKLKAKKGASSSSTAESKVEDETFTNDIEPTTALNSTSTQETEKSRASVTQRPSSLQQEIDDSDEL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
134	N-linked_Glycosylation	FVISDEENYSLEEII EEECCCCCCCHHHHH	-
247	N-linked_Glycosylation	SSLGKKQNITRIRAL CCCCCCCCCHHHHHH	-
359	N-linked_Glycosylation	NKALKKANLTFSEIN HHHHHHCCCCHHHCC	-
457	N-linked_Glycosylation	TPYGMQHNVTIHNVS CCCCCCCCEEEEECC	-
462	N-linked_Glycosylation	QHNVTIHNVSTIGKH CCCEEEEECCCCCCC	-
488	N-linked_Glycosylation	IGEFTLSNITDVEKV EEEEEECCCCCHHHH	-
555	N-linked_Glycosylation	DESGLRNNESYPIGF CCCCCCCCCCCCCCE	-
632	N-linked_Glycosylation	EETKILKNDSVESYD HHCCCCCCCCCCCCC	-
678	N-linked_Glycosylation	FDQAKQFNTSLENFK HHHHHHHHHHHHHHH	-
733	N-linked_Glycosylation	KLGNQYYNDTQWLKD HHCCCCCCCCHHHHH	-
817	N-linked_Glycosylation	IEPTTALNSTSTQET CCCCCCCCCCCCCHH	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LHS1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LHS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LHS1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of LHS1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LHS1_SCHPO

Related Literatures of Post-Translational Modification