LGC50_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LGC50_CAEEL
• UniProt AC: P41849
• Protein Name: Ligand-gated ion channel 50
• Gene Name: lgc-50
• Organism: Caenorhabditis elegans.
• Sequence Length: 491
• Subcellular Localization: Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .
• Protein Sequence: MRFLLVLQLVFFYFSAATTNSPKKCSRNSINLGKLIDTLLTDYDTHLLPEAEGVNVTIELHVQGVSGISEITGDFSLDVMYSEIWQDPRLSFKHLNVCATNITLKSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYENGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTDEVRLMWHDVPITMMEKVELPDFDLIGWSTDHQRLEYPNGIWDRAKVKFTFARRYGFYLFQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLDVWMIFSVIFIFCTLVELAIVCQLNRWERERQIGSKVLGHWLNQIRKTRKKESKADEGGGGGVGGLLRKRIPVLAQLKAAATDSNSGAATAMTTAIQPPNTNLNSITNSDNSKLVANNFTSIEHETYAYEKKRGFSHCFQRFVYAICPPDRDWTITSVQVDRCSMIMFPLSFLIFNVVYWSIYFMKMDRPM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
55	N-linked_Glycosylation	LPEAEGVNVTIELHV CCCCCCCCEEEEEEE	35.75	-
101	N-linked_Glycosylation	HLNVCATNITLKSDF HCCEEEEEEEECHHH	13.51	-
418	N-linked_Glycosylation	NSKLVANNFTSIEHE CCCEEECCCCCCCCC	31.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LGC50_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LGC50_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LGC50_CAEEL !!

Protein-Protein Interaction

Oops, there are no PPI records of LGC50_CAEEL !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.