LENG8_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LENG8_MOUSE
• UniProt AC: Q8CBY3
• Protein Name: Leukocyte receptor cluster member 8 homolog
• Gene Name: Leng8
• Organism: Mus musculus (Mouse).
• Sequence Length: 785
• Protein Sequence: MAANVGDQRAADWSSQYSMVTGNSRENGMETPMHENPEWEKARQALASISKAGATSSSKASSSGPVASAQYVSQAEASALQQQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMASSYGSATAQQPSAPQHQGTLNQPPVPGMDESMAYQASPQQLPAAQPPQPSNSQHGTHSLSNGPQPGTAPSTQHSQAGAPTGQAYGPHSYSEPAKPKKGQQLWTRMKPAPGTGGLKFNIQKRPFAVTSQSFSSNSEGQHSSFGPQPNSENTQNRSGPSGRGNLSGKPDDWPQDMKEYVERCFTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAPSSLHPSRGAGSVTRGGGAQSQRGTPGAGGAGRARGSSFTKFGNRNVFMKDNSSSSSTDSRSRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRGKRHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHSRRLRLEPLVLQMSNLESSGADPDWQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKSHWKEKQDYAFACEQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAENLAGNVGEFTAYRILYYIFTKNSGDITTELAYLTREMKADPCVAHALALRAAWALGNYHRFFRLYCHAPCMSGYLVDKFADRERKAALKAMIKTYVALHSAAFCAVALPRPLRILVSLQLLCWSPLPVPCS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAANVGDQR ------CCCCCCCCC	14.03	-
31	Phosphorylation	SRENGMETPMHENPE CCCCCCCCCCCCCHH	19.61	-
333	Phosphorylation	LQDGSAYTIDWSREP CCCCCEEEEECCCCC	16.51	26643407
337	Phosphorylation	SAYTIDWSREPLPGL CEEEEECCCCCCCCC	24.02	26643407
345	Phosphorylation	REPLPGLTREPVAES CCCCCCCCCCCCCCC	38.61	26643407
352	Phosphorylation	TREPVAESPKKKRWE CCCCCCCCCCCCCCC	32.08	27087446
375	Methylation	RGAGSVTRGGGAQSQ CCCCCCCCCCCCCCC	39.33	30987795
426	Phosphorylation	DSRSRSSSRSPTRHF CCCCCCCCCCCCCCC	37.72	29514104
428	Phosphorylation	RSRSSSRSPTRHFRR CCCCCCCCCCCCCCC	32.35	23384938
464	Methylation	RNPPPKGRGGRGAHM CCCCCCCCCCCCCCC	50.98	30987777
467	Methylation	PPKGRGGRGAHMDRG CCCCCCCCCCCCCCC	41.78	30987783
473	Methylation	GRGAHMDRGRGRAQR CCCCCCCCCCCHHHH	29.18	30987789

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LENG8_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LENG8_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LENG8_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of LENG8_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.