LDHA_CHICK - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LDHA_CHICK
• UniProt AC: P00340
• Protein Name: L-lactate dehydrogenase A chain
• Gene Name: LDHA
• Organism: Gallus gallus (Chicken).
• Sequence Length: 332
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MSLKDHLIHNVHKEEHAHAHNKISVVGVGAVGMACAISILMKDLADELTLVDVVEDKLKGEMLDLQHGSLFLKTPKIISGKDYSVTAHSKLVIVTAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPDCKLLIVSNPVDILTYVAWKISGFPKHRVIGSGCNLDSARFRHLMGERLGIHPLSCHGWIVGEHGDSSVPVWSGVNVAGVSLKALHPDMGTDADKEHWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAETIMKNLRRVHPISTAVKGMHGIKDDVFLSVPCVLGSSGITDVVKMILKPDEEEKIKKSADTLWGIQKELQF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLKDHLIH ------CCHHHHHHC	44.09	1956339
239	Phosphorylation	KQVVDSAYEVIKLKG HHHHHHHHHHHHCCC	18.06	6330085
243	Acetylation	DSAYEVIKLKGYTSW HHHHHHHHCCCCCHH	49.69	6793082

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
2	S	Phosphorylation	Kinase	PKC-FAMILY	-	GPS
2	S	Phosphorylation	Kinase	PKC_GROUP	-	PhosphoELM

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LDHA_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LDHA_CHICK !!

Protein-Protein Interaction

Oops, there are no PPI records of LDHA_CHICK !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.