LCF2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LCF2_SCHPO
• UniProt AC: Q9P7D7
• Protein Name: Long-chain-fatty-acid--CoA ligase 2
• Gene Name: lcf2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 689
• Subcellular Localization: Golgi apparatus . Vacuole membrane ; Peripheral membrane protein .
• Protein Description: Esterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Plays an important role in the determination of viability in the stationary phase..
• Protein Sequence: MDIKDYYCVETKDSKQPGESYIYRSIHSAGKLLDTPEDGVSTVYDLLCTAAKNHGEKQAMGSRKLIKENREEREIIRKVDNEEVVEKKLWTTYELGPYEYISFNKVYEIALALGSGLVASGITSETTMLFFAATSAKWFTTAQGCSSQAIPIVTAYETLGEDGIYTSLDECKSRAIFTDPNLIPKLLGPLKQSTWVKLIVCSSTPSEDLVELVKSTAPDVEIITYDNLLSLGKEKPQPPHPPKADDICCYMYTSGSTGKPKGVVLLHRNIIAALGGINRILSQHINVKDYVLAYLPLAHIFEFIFEMCCLYWGGVLGYASPRTLTDASVVNCKGDLTEFRPTVLIGVPAVYELIKKGILAKVSSMPAHRQKVFSGSLSLKQYLIERNLPGSAALDAIVFNKVKAATGGRLRYCISGGAALAASTQAFLSSCICPVLPGYGLTETCAGSFVLSPEQWHLYANTVGFPIPSIEFKLVDIPDLGYYTDSSPPRGEVWIRGPAVCNGYLNRPEDNKAAFTEDGWFKTGDVGEIAKGNTLRLIDRKKNIVKSLNGEYIALEKIEAQFFTSPLVSNVCAYADVNHAKPVVIVNPDENGLRTYLTKNSGSSFNGNPNDTLTNLCKDSGVQHLILKELINIGKQQRLASIEIPEGVVLSDFEWTAENNFLTASRKVKRQVIVAHYSDEIQKAYSKKH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
547	Phosphorylation	RKKNIVKSLNGEYIA CCCCHHHHHCCCEEE	19.03	25720772
601	Phosphorylation	RTYLTKNSGSSFNGN EEEEECCCCCCCCCC	41.42	25720772
603	Phosphorylation	YLTKNSGSSFNGNPN EEECCCCCCCCCCCC	31.42	25720772
604	Phosphorylation	LTKNSGSSFNGNPND EECCCCCCCCCCCCC	26.68	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LCF2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LCF2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LCF2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LCF1_SCHPO	lcf1	genetic	18071249

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.