LCE5A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LCE5A_HUMAN
• UniProt AC: Q5TCM9
• Protein Name: Late cornified envelope protein 5A
• Gene Name: LCE5A
• Organism: Homo sapiens (Human).
• Sequence Length: 118
• Protein Description: Precursors of the cornified envelope of the stratum corneum..
• Protein Sequence: MSCQQSQQQCQPPPKCTPKCPPKCTPKCPPKCPPKCPPQCSAPCPPPVSSCCGSSSGGCCSSEGGGCCLSHHRPRQSLRRRPQSSSCCGSGSGQQSGGSSCCHSSGGSGCCHSSGGCC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	CQPPPKCTPKCPPKC CCCCCCCCCCCCCCC	31.73	-
41	Phosphorylation	PKCPPQCSAPCPPPV CCCCCCCCCCCCCCC	29.96	28787133
49	Phosphorylation	APCPPPVSSCCGSSS CCCCCCCHHHCCCCC	24.35	28787133
104	Phosphorylation	GGSSCCHSSGGSGCC CCCCCCCCCCCCCCC	19.43	30576142
113	Phosphorylation	GGSGCCHSSGGCC-- CCCCCCCCCCCCC--	19.43	30576142
114	Phosphorylation	GSGCCHSSGGCC--- CCCCCCCCCCCC---	18.62	30576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LCE5A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LCE5A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LCE5A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of LCE5A_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.