LACS4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LACS4_ARATH
• UniProt AC: Q9T0A0
• Protein Name: Long chain acyl-CoA synthetase 4
• Gene Name: LACS4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 666
• Protein Description: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate..
• Protein Sequence: MSQQKKYIFQVEEGKEGSDGRPSVGPVYRSIFAKDGFPDPIEGMDSCWDVFRMSVEKYPNNPMLGRREIVDGKPGKYVWQTYQEVYDIVMKLGNSLRSVGVKDEAKCGIYGANSPEWIISMEACNAHGLYCVPLYDTLGADAVEFIISHSEVSIVFVEEKKISELFKTCPNSTEYMKTVVSFGGVSREQKEEAETFGLVIYAWDEFLKLGEGKQYDLPIKKKSDICTIMYTSGTTGDPKGVMISNESIVTLIAGVIRLLKSANEALTVKDVYLSYLPLAHIFDRVIEECFIQHGAAIGFWRGDVKLLIEDLAELKPTIFCAVPRVLDRVYSGLQKKLSDGGFLKKFIFDSAFSYKFGYMKKGQSHVEASPLFDKLVFSKVKQGLGGNVRIILSGAAPLASHVESFLRVVACCHVLQGYGLTESCAGTFVSLPDELGMLGTVGPPVPNVDIRLESVPEMEYDALASTARGEICIRGKTLFSGYYKREDLTKEVLIDGWLHTGDVGEWQPDGSMKIIDRKKNIFKLSQGEYVAVENIENIYGEVQAVDSVWVYGNSFESFLIAIANPNQHILERWAAENGVSGDYDALCQNEKAKEFILGELVKMAKEKKMKGFEIIKAIHLDPVPFDMERDLLTPTFKKKRPQLLKYYQSVIDEMYKTINAKFASRG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
338	Phosphorylation	SGLQKKLSDGGFLKK HHHHHHHCCCCHHHH	42.99	24894044
364	Phosphorylation	GYMKKGQSHVEASPL CCCCCCCCCCCCCHH	37.86	19880383
580	Phosphorylation	WAAENGVSGDYDALC HHHHHCCCCCHHHHH	27.61	19880383
633	Phosphorylation	DMERDLLTPTFKKKR CCCHHCCCHHHHHHC	27.81	25561503
635	Phosphorylation	ERDLLTPTFKKKRPQ CHHCCCHHHHHHCHH	42.74	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LACS4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LACS4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LACS4_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LACS9_ARATH	LACS9	genetic	25540329

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.