L10K_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: L10K_HUMAN
• UniProt AC: Q9UNZ5
• Protein Name: Leydig cell tumor 10 kDa protein homolog
• Gene Name: C19orf53
• Organism: Homo sapiens (Human).
• Sequence Length: 99
• Protein Description: May have a potential role in hypercalcemia of malignancy..
• Protein Sequence: MAQGQRKFQAHKPAKSKTAAAASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSSLPKKLALLKAPAKKKGAAAATSSKTPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Acetylation	QRKFQAHKPAKSKTA CHHHHCCCCCCCHHH	50.08	26051181
15	Ubiquitination	FQAHKPAKSKTAAAA HHCCCCCCCHHHHHH	62.10	24816145
17	Acetylation	AHKPAKSKTAAAASE CCCCCCCHHHHHHHH	41.29	26051181
23	Phosphorylation	SKTAAAASEKNRGPR CHHHHHHHHHCCCCC	44.36	23532336
25	Acetylation	TAAAASEKNRGPRKG HHHHHHHHCCCCCCC	49.83	26051181
25	Ubiquitination	TAAAASEKNRGPRKG HHHHHHHHCCCCCCC	49.83	33845483
40	Ubiquitination	GRVIAPKKARVVQQQ CEECCCCCHHHHHHH	40.13	24816145
48	Ubiquitination	ARVVQQQKLKKNLEV HHHHHHHHHHHHHCH	58.92	33845483
51	Ubiquitination	VQQQKLKKNLEVGIR HHHHHHHHHHCHHHH	76.76	29967540
60	Ubiquitination	LEVGIRKKIEHDVVM HCHHHHHHCCHHHHH	43.40	16196087
68	Ubiquitination	IEHDVVMKASSSLPK CCHHHHHHCCCCCCH	33.24	16196087
70	Phosphorylation	HDVVMKASSSLPKKL HHHHHHCCCCCCHHH	18.23	26699800
71	Phosphorylation	DVVMKASSSLPKKLA HHHHHCCCCCCHHHH	40.53	26699800
72	Phosphorylation	VVMKASSSLPKKLAL HHHHCCCCCCHHHHH	46.31	26699800
76	Ubiquitination	ASSSLPKKLALLKAP CCCCCCHHHHHHCCC	36.73	16196087
81	Ubiquitination	PKKLALLKAPAKKKG CHHHHHHCCCHHHCC	53.85	33845483
85	Ubiquitination	ALLKAPAKKKGAAAA HHHCCCHHHCCCCHH	54.69	22817900
86	Ubiquitination	LLKAPAKKKGAAAAT HHCCCHHHCCCCHHC	59.55	22817900
87	Ubiquitination	LKAPAKKKGAAAATS HCCCHHHCCCCHHCC	53.74	22817900
93	Phosphorylation	KKGAAAATSSKTPS- HCCCCHHCCCCCCC-	28.89	27251275
94	Phosphorylation	KGAAAATSSKTPS-- CCCCHHCCCCCCC--	25.72	27251275
95	Phosphorylation	GAAAATSSKTPS--- CCCHHCCCCCCC---	35.87	29396449
96	Ubiquitination	AAAATSSKTPS---- CCHHCCCCCCC----	65.31	33845483
97	Phosphorylation	AAATSSKTPS----- CHHCCCCCCC-----	30.61	25849741
99	Phosphorylation	ATSSKTPS------- HCCCCCCC-------	59.07	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of L10K_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of L10K_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of L10K_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of L10K_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.