dbPTM

KT33A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KT33A_HUMAN
UniProt AC	O76009
Protein Name	Keratin, type I cuticular Ha3-I
Gene Name	KRT33A
Organism	Homo sapiens (Human).
Sequence Length	404
Subcellular Localization
Protein Description
Protein Sequence	MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Phosphorylation	LNDRLASYLEKVRQL HHHHHHHHHHHHHHH	17.17	-
109	Phosphorylation	SYQSYFKTIEELQQK HHHHHHHHHHHHHHH	24.58	-
150	Phosphorylation	TKYETELSLRQLVES HHHHHHHHHHHHHHH	18.44	24719451
261	Phosphorylation	LNKQVVSSSEQLQSY HHHHHCCCHHHHHHH	26.70	24719451
268	Phosphorylation	SSEQLQSYQAEIIEL CHHHHHHHHHHHHHH	9.97	24719451
278	Phosphorylation	EIIELRRTVNALEIE HHHHHHHHHHHHHHH	16.21	20068231
299	Phosphorylation	LRDSLENTLTESEAR CHHHHHHHCCHHHHH	26.19	22817900
301	Phosphorylation	DSLENTLTESEARYS HHHHHHCCHHHHHHH	35.11	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KT33A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KT33A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KT33A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KT33A_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KT33A_HUMAN

Related Literatures of Post-Translational Modification