KRT37_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KRT37_HUMAN
• UniProt AC: O76014
• Protein Name: Keratin, type I cuticular Ha7
• Gene Name: KRT37
• Organism: Homo sapiens (Human).
• Sequence Length: 449
• Protein Sequence: MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGSTPLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCTSCPSCGPVTGGSPSGHGASMGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTSFYSTSS ------CCCCCCCCC	27.78	24043423
3	Phosphorylation	-----MTSFYSTSSC -----CCCCCCCCCC	22.38	24043423
5	Phosphorylation	---MTSFYSTSSCPL ---CCCCCCCCCCCC	15.71	24043423
6	Phosphorylation	--MTSFYSTSSCPLG --CCCCCCCCCCCCC	21.58	24043423
7	Phosphorylation	-MTSFYSTSSCPLGC -CCCCCCCCCCCCCC	17.18	24043423
8	Phosphorylation	MTSFYSTSSCPLGCT CCCCCCCCCCCCCCC	24.81	24043423
9	Phosphorylation	TSFYSTSSCPLGCTM CCCCCCCCCCCCCCC	21.60	24043423
15	Phosphorylation	SSCPLGCTMAPGARN CCCCCCCCCCCCCCE	17.99	24043423
59	Phosphorylation	ANRVRVGSTPLGRPS HCCCEECCCCCCCCC	24.80	-
60	Phosphorylation	NRVRVGSTPLGRPSL CCCEECCCCCCCCCC	19.32	-
66	Phosphorylation	STPLGRPSLCLPPTS CCCCCCCCCCCCCCC	30.29	-
75	Phosphorylation	CLPPTSHTACPLPGT CCCCCCCCCCCCCCC	29.71	-
145	Phosphorylation	ERSKCHESTVCPDYQ HHHCCCCCCCCCHHH	11.50	-
154	Phosphorylation	VCPDYQSYFRTIEEL CCCHHHHHHHHHHHH	4.99	22817900
157	Phosphorylation	DYQSYFRTIEELQQK HHHHHHHHHHHHHHH	23.88	-
195	Phosphorylation	DFRIKLESERSLHQL CCEEEEHHHCHHHHH	49.06	23312004
218	Phosphorylation	QKLLDDATLAKADLE HHHHCHHHHHHHHHH	33.95	20068231
355	Phosphorylation	LCEAEDRYGTELAQM HHHHHHHHHHHHHHH	40.50	22817900
374	Phosphorylation	SNLEEQLSEIRADLE HHHHHHHHHHHHHHH	30.58	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KRT37_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KRT37_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KRT37_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of KRT37_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.