dbPTM

KRT35_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KRT35_MOUSE
UniProt AC	Q497I4
Protein Name	Keratin, type I cuticular Ha5 {ECO:0000250\|UniProtKB:Q92764}
Gene Name	Krt35 {ECO:0000312\|MGI:MGI:1858899}
Organism	Mus musculus (Mouse).
Sequence Length	455
Subcellular Localization
Protein Description
Protein Sequence	MASKCLKASFSSGSLKSPGKAGGGSTRVSNMYSSSSCKLPSPSRGARSFSVCSAGLGRGNYRVSSCLPALCLPTGGFATSYGTGGGWFGEGILTGNEKETMQSLNDRLASYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTMEELQKKTLCSKAENARLVVQIDNAKLAADDFRTKYETEVSLRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLDEMRCQYETLVENNRRDAEDWYDTQTEELNQQVVSSSEQLQSCQSDIIELRRTVNSLEIELQAQQSMRDALDSTLAETEGRYSSQLAQMQCMIGNVESQLGEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSSSKSCLPCLPAVSCSTGAARTTCSPRPVCVPCPGGRF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
103	Phosphorylation	NEKETMQSLNDRLAS CHHHHHHHHHHHHHH	20.51	-
223	Phosphorylation	DLEAQVESLKEELLC HHHHHHHHHHHHHHH	45.98	23737553
349	Phosphorylation	AETEGRYSSQLAQMQ HHHCCCCHHHHHHHH	15.39	28494245
350	Phosphorylation	ETEGRYSSQLAQMQC HHCCCCHHHHHHHHH	21.93	28494245

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KRT35_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KRT35_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KRT35_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KRT35_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KRT35_MOUSE

Related Literatures of Post-Translational Modification