dbPTM

KRA97_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KRA97_HUMAN
UniProt AC	A8MTY7
Protein Name	Keratin-associated protein 9-7 {ECO:0000305}
Gene Name	KRTAP9-7 {ECO:0000312\|HGNC:HGNC:18915}
Organism	Homo sapiens (Human).
Sequence Length	169
Subcellular Localization
Protein Description	In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity)..
Protein Sequence	MTHCCSPCCQPTCCRTTCWKPTTVTTCSSTPCCQPSCCVSSCCQPCCHPTCCQNTCCRTTCCQPTCVTSCCQPSCCSTPCCQPICCGSSCCGQTSCGSSCCQPSSCAPIYCRRTCYHPTSVYLPGCLNQSCGSSCCQPCCRPACCETTCCRTTCFQPTCVTSCCQPACC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTHCCSPCC ------CCCCCCCCC	24.50	24043423
6	Phosphorylation	--MTHCCSPCCQPTC --CCCCCCCCCCCEE	26.77	24043423
12	Phosphorylation	CSPCCQPTCCRTTCW CCCCCCCEEECCCCC	9.81	24043423
152	Phosphorylation	CETTCCRTTCFQPTC CCCCCCCCCCCCCEE	17.63	24144214
153	Phosphorylation	ETTCCRTTCFQPTCV CCCCCCCCCCCCEEE	7.62	24144214

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KRA97_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KRA97_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KRA97_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KRA97_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KRA97_HUMAN

Related Literatures of Post-Translational Modification