KRA56_HUMAN - dbPTM
KRA56_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KRA56_HUMAN
UniProt AC Q6L8G9
Protein Name Keratin-associated protein 5-6
Gene Name KRTAP5-6
Organism Homo sapiens (Human).
Sequence Length 129
Subcellular Localization
Protein Description In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins..
Protein Sequence MGCCGCSGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCCCVPACSCTSCGSCGGSKGCCGSCGGSKGGCGSCGGSKGGCGSCGCSQCSCCKPCYCSSGCGSSCCQSSCCKPCCSQASCCVPICCQCKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
52PhosphorylationCSCTSCGSCGGSKGC
CCCCCCCCCCCCCCC
17.57-
56PhosphorylationSCGSCGGSKGCCGSC
CCCCCCCCCCCCCCC
15.91-
62PhosphorylationGSKGCCGSCGGSKGG
CCCCCCCCCCCCCCC
8.8224114839
66PhosphorylationCCGSCGGSKGGCGSC
CCCCCCCCCCCCCCC
17.2624114839
67UbiquitinationCGSCGGSKGGCGSCG
CCCCCCCCCCCCCCC
63.7023503661
72PhosphorylationGSKGGCGSCGGSKGG
CCCCCCCCCCCCCCC
17.4224114839
76PhosphorylationGCGSCGGSKGGCGSC
CCCCCCCCCCCCCCC
17.2624114839
77UbiquitinationCGSCGGSKGGCGSCG
CCCCCCCCCCCCCCC
63.7023503661
82PhosphorylationGSKGGCGSCGCSQCS
CCCCCCCCCCCCCCC
16.0630576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KRA56_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KRA56_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KRA56_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of KRA56_HUMAN !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KRA56_HUMAN

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Related Literatures of Post-Translational Modification

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