KN14A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KN14A_ARATH
• UniProt AC: Q9LX99
• Protein Name: Kinesin-like protein KIN-14A {ECO:0000305}
• Gene Name: KIN14A {ECO:0000305}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1273
• Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome. Cell membrane. Cytoplasm, cytoskeleton, phragmoplast. Localizes to the spindle apparatus and condensed chromosomes in mitotic cells. Localizes in the forming cell plate and the cortical division
• Protein Description: Kinesin-like protein required for chloroplast movements and anchor to the plasma membrane. Mediates chloroplast movement via chloroplast actin (cp-actin) filaments. Required for the chloroplast avoidance response under high intensity blue light. [PubMed: 20418504]
• Protein Sequence: MADQRSKTNRWNWEVSGFEPRKSSSNASFAESTGHRTTGPLLRRNSISTPSLPPKQAIASKVNGLKEKVKLAKEDYLELRQEATDLQEYSNAKLDRVTRYLGVLAEKSRKLDQFVLETEARISPLINEKKRLFNDLLTAKGNIKVFCRARPLFEDEGPSVIEFPGDCTICVNTSDDTLSNPKKDFEFDRVYGPHVGQAALFSDVQPFVQSALDGSNVSILSYGQTNAGKTYTMEGSNHDRGLYARCFEELFDLANSDSTSTSRFSFSLSVFEIYNEQIRDLLSETQSNLPNINMDLHESVIELGQEKVDNPLEFLGVLKSAFLNRGNYKSKFNVTHLIVSIHIYYSNTITGENIYSKLSLVDLAGSEGLIMENDSGDHVTDLLHVMNSISALGDVLSSLTSGKDSIPYDNSILTRVLADSLGGSSKTLMIVNICPSVQTLSETISCLNYAARARNTVPSLGNRDTIKKWRDVASDARKELLEKERENQNLKQEVVGLKKALKDANDQCVLLYSEVQRAWKVSFTLQSDLKSENIMLVDKHRLEKEQNSQLRNQIAQFLQLDQEQKLQMQQQDSAIQNLQAKITDLESQVSEAVRSDTTRTGDALQSQDIFSPIPKAVEGTTDSSSVTKKLEEELKKRDALIERLHEENEKLFDRLTERSMAVSTQVLSPSLRASPNIQPANVNRGEGYSAEAVALPSTPNKNNGAITLVKSGTDLVKTTPAGEYLTAALNDFDPEEYEGLAAIADGANKLLMLVLAAVIKAGASREHEILAEIRDSVFSFIRKMEPRRVMDTMLVSRVRILYIRSLLARSPELQTIRVSPVECFLEKPNTGRSKSTSRGSSPGRSPVRYLDTQIHGFKVNIKAERRNKLASVVSRMRGLEQDAGRQQVTGVKLREMQDEAKSFAIGNKALAALFVHTPAGELQRQIRLWLAENFEFLSVTSDDVSGGNGGQLELLSTAIMDGWMAGLGAAVPPHTDALGQLLSEYAKRVYTSQMQHMKDIAGTLAAEEAEDAGQVSKLRSALESVDHKRRKILQQMKSDAALLNLEEGSSPIPNPSTAAEDSRLASLISLDGILKQVKEITRQASVHVLSKSKKKALLESLDELTERMPSLLDIDHPCAQREIATAHQLVETIPEQEDTNILEQSHDRRPSLESISSGETDVSQWNVLQFNTGSSAPFIIKCGGNNNSELVIKADARVQEPKGGEIVRVVPRPSVLVNMSLEEMKQMFVQLPEALSLLALARTADGTRARYSRLYKTLAMKVPSLKDLVSELE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	SGFEPRKSSSNASFA CCCCCCCCCCCCCHH		25561503
24	Phosphorylation	GFEPRKSSSNASFAE CCCCCCCCCCCCHHH		25561503
25	Phosphorylation	FEPRKSSSNASFAES CCCCCCCCCCCHHHH		25561503
28	Phosphorylation	RKSSSNASFAESTGH CCCCCCCCHHHHCCC		27545962
32	Phosphorylation	SNASFAESTGHRTTG CCCCHHHHCCCCCCC		25561503
33	Phosphorylation	NASFAESTGHRTTGP CCCHHHHCCCCCCCC		25561503
46	Phosphorylation	GPLLRRNSISTPSLP CCCCCCCCCCCCCCC		30291188
48	Phosphorylation	LLRRNSISTPSLPPK CCCCCCCCCCCCCHH		23776212
49	Phosphorylation	LRRNSISTPSLPPKQ CCCCCCCCCCCCHHH		23776212
51	Phosphorylation	RNSISTPSLPPKQAI CCCCCCCCCCHHHHH		23776212
123	Phosphorylation	LETEARISPLINEKK HHCHHHHHHHHCHHH		25561503
424	Phosphorylation	LADSLGGSSKTLMIV HHHHCCCCCCEEEEE		24243849
425	Phosphorylation	ADSLGGSSKTLMIVN HHHCCCCCCEEEEEE		24243849
606	Phosphorylation	RTGDALQSQDIFSPI CCCHHHHCCCCCCCC		17317660
611	Phosphorylation	LQSQDIFSPIPKAVE HHCCCCCCCCCCCCC		19880383
659	Phosphorylation	FDRLTERSMAVSTQV HHHHHHHHHHHHHCC		19376835
663	Phosphorylation	TERSMAVSTQVLSPS HHHHHHHHHCCCCHH		19376835
664	Phosphorylation	ERSMAVSTQVLSPSL HHHHHHHHCCCCHHH		19376835
668	Phosphorylation	AVSTQVLSPSLRASP HHHHCCCCHHHCCCC		30291188
670	Phosphorylation	STQVLSPSLRASPNI HHCCCCHHHCCCCCC		19376835
674 (in isoform 2)	Phosphorylation	-		30291188
674	Phosphorylation	LSPSLRASPNIQPAN CCHHHCCCCCCCCCC		30291188
697	Phosphorylation	AEAVALPSTPNKNNG CEEEECCCCCCCCCC		17317660
698	Phosphorylation	EAVALPSTPNKNNGA EEEECCCCCCCCCCC		17317660
835	Phosphorylation	PNTGRSKSTSRGSSP CCCCCCCCCCCCCCC		29654922
836	Phosphorylation	NTGRSKSTSRGSSPG CCCCCCCCCCCCCCC		29654922
837	Phosphorylation	TGRSKSTSRGSSPGR CCCCCCCCCCCCCCC		29654922
840	Phosphorylation	SKSTSRGSSPGRSPV CCCCCCCCCCCCCCC		19376835
841	Phosphorylation	KSTSRGSSPGRSPVR CCCCCCCCCCCCCCE		19376835
845	Phosphorylation	RGSSPGRSPVRYLDT CCCCCCCCCCEEEEC		19376835
1038	Phosphorylation	KILQQMKSDAALLNL HHHHHHHHHHHHHCC		23776212
1049	Phosphorylation	LLNLEEGSSPIPNPS HHCCCCCCCCCCCCC		23776212
1050	Phosphorylation	LNLEEGSSPIPNPST HCCCCCCCCCCCCCC		19880383
1056	Phosphorylation	SSPIPNPSTAAEDSR CCCCCCCCCHHHHHH		23776212
1057	Phosphorylation	SPIPNPSTAAEDSRL CCCCCCCCHHHHHHH		23776212
1062	Phosphorylation	PSTAAEDSRLASLIS CCCHHHHHHHHHHHC		23776212
1100	Phosphorylation	KKKALLESLDELTER HHHHHHHHHHHHHHH		29797451
1264	Phosphorylation	TLAMKVPSLKDLVSE HHHHHCCCHHHHHHH		30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KN14A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KN14A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KN14A_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of KN14A_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.