dbPTM

KMS1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KMS1_ARATH
UniProt AC	Q5XF36
Protein Name	Vacuole membrane protein KMS1 {ECO:0000303\|PubMed:21294794}
Gene Name	KMS1 {ECO:0000303\|PubMed:21294794}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	416
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein .
Protein Description	Involved in the early secretory pathway. Required for the correct export of secretory products from the endoplasmic reticulum (ER) and involved in the maintenance of ER integrity..
Protein Sequence	MGSAGVASSSSDVAISALREKHEKEVENLTLTTQPLNTLKLFVEATIQYIKRSISYLLAHGGWFILITTLLVVSGGLLVTVDGPHGKHVEEVLEYVRYGLWWIALGVASSIGLGSGLHTFVLYLGPHIALFTLKATLCGRVDLKSAPYDTIQLKRVPSWLDKSCSEFGPPLMISAAGSRVPLTSILPQVQLEAILWGIGTALGELPPYFISRAASISGSTVDGMEELDGSSTEDSGFMATHLNRVKRWLLTHSQHLNFFTVLVLASVPNPLFDLAGIMCGQFGIPFWEFFLATLIGKAIIKTHIQTIFIICVCNNQLLDWMENELIWILSHVPGLASMLPGLTAKLHAMKEKYIDAPSPVPSHIKVKKWDFSFASIWNGIVWLMLLNFFVKIVTATAQRHLKKKQEKEMATLTHSD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
2	Acetylation	------MGSAGVASS ------CCCCCCCCC	22223895
3	Phosphorylation	-----MGSAGVASSS -----CCCCCCCCCH	30407730
8	Phosphorylation	MGSAGVASSSSDVAI CCCCCCCCCHHHHHH	30407730
9	Phosphorylation	GSAGVASSSSDVAIS CCCCCCCCHHHHHHH	30407730
10	Phosphorylation	SAGVASSSSDVAISA CCCCCCCHHHHHHHH	24894044
11	Phosphorylation	AGVASSSSDVAISAL CCCCCCHHHHHHHHH	24894044
158	Phosphorylation	IQLKRVPSWLDKSCS EEEECCCHHHCCHHH	25561503
358	Phosphorylation	EKYIDAPSPVPSHIK HHHCCCCCCCCCCCE	28295753
362	Phosphorylation	DAPSPVPSHIKVKKW CCCCCCCCCCEECCC	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KMS1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KMS1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KMS1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
NIP11_ARATH	NLM1	physical	21798944
NAC89_ARATH	NAC089	physical	21798944

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KMS1_ARATH

Related Literatures of Post-Translational Modification