dbPTM

KLH36_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KLH36_MOUSE
UniProt AC	Q8R124
Protein Name	Kelch-like protein 36
Gene Name	Klhl36
Organism	Mus musculus (Mouse).
Sequence Length	613
Subcellular Localization
Protein Description	Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins..
Protein Sequence	MEASKQMRVSRPYKISESSKVYHWPDHSTAVLQRLNEQRLHGLFCDVVLVVEEQQVPAHRNLLAVCSDYFNSMFTLGMREAFQKEVELVGTSYVGLKAVVDFLYSSELELDGSNIDYILETAHLLQIWTVVDFCCEYLEQEVSEDNYLYLQELASIYSLKRLDAFIDSFVLSHFSTLSFTPDFLQSISVQKLCVYLSSGQVQHKWEYDLLQVALQWLTQQPEREVHTRRVLENIRFPLFPEDILLQRVKLAMCSLLPSEANGEGFVEEAMHYHNSLVAQPVLQTKRTLLRSEECLLFVGGEVSERCLELSDDTCYLDTKNEQWVKETSLPARRSHHCVAVLGGFIFIAGGSFSRDNGGNAASNLLYRYDPRRKQWIKVASMNQRRVDFYLASIEDMLVAVGGRNENGALSSVETYSPKTNSWTYVAGLPRFTYGHAGTIYKDFVYISGGHDYQIGPYRKNLLCYDHRTDVWEERRPMTTARGWHSMCSLGDSIYSIGGSDDHMESMERFDVLGVEAYSPQCNQWTRVAPLLQANSESGVAVWQGRIYILGGYSWESTAFSRAVQVYDSEANRWSRGPDLPNAIAGVSACVCALNPRLEEKKKRNKDKCQDRGQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
16	Phosphorylation	VSRPYKISESSKVYH CCCCEEECCCCCCCC	27.55	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KLH36_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KLH36_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KLH36_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KLH36_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KLH36_MOUSE

Related Literatures of Post-Translational Modification