dbPTM

KLD10_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KLD10_DROME
UniProt AC	A1ZB86
Protein Name	Kelch domain-containing protein 10 homolog
Gene Name	slim
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	609
Subcellular Localization
Protein Description	Activates the Pk92B/DASK1-MAPK signaling cascade..
Protein Sequence	MNILNPGKFKCIVFDQLRHTWTFLLFICDFLAKIYRTPRITAHQEQLANHNNNNNNNNDLIMEQDMPEEEVGQPEEALPQQDNGEVVDRFNAIQAAVELMDAASDLDEEEEEEDDDVDVDVDYGDTDSESEFEEMYSDEWTSSSDELDEGTELSKSVLNVFLSSDKQQSQMAGQIPMYAFQPLRLVKCQYRDKHIPGGFPLARSGHRIIASNSHLYSLGGYNPRSAMSASRHGRCLLFQELWSYNFATRTWRLELNAGNAANMPVELASNALTIHNNVLISHGGTGYPFGVSCSNDCYVYRTASAGATPGVDRLQVKGDLPTAQYGPGIVIHKHFLYTIGGTTGFDYTCDVYRLDLRTGIWENVYISRPEMRDDPEGRYRHEVVYDGKHIFVLGGGTSHSVYDLQRIPAYNLEANCWDYFETYPDQRAADADDGNRGYPKPRKCFSCVQHQSSTGDIEAFITGGLQGDFSTYFSDIWKLNLRTKHWYRIETAILPRPLYFHSAAHSDNGCMYVFGGIEYIDKEMRRRNDLYKMWMTVPKLSEMCWDAITYYNDNLDLYDRKTLLEAGIPKRFTERLPPQRRRRLDTSQPDPSMLISLYSNPKRARSSTQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
156	Phosphorylation	EGTELSKSVLNVFLS CCHHHCHHHHHHHHC		29892262

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KLD10_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KLD10_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KLD10_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
MK14A_DROME	p38a	genetic	23102700

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KLD10_DROME

Related Literatures of Post-Translational Modification