dbPTM

KIF17_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KIF17_MOUSE
UniProt AC	Q99PW8
Protein Name	Kinesin-like protein KIF17
Gene Name	Kif17
Organism	Mus musculus (Mouse).
Sequence Length	1038
Subcellular Localization	Cytoplasm, cytoskeleton . Cell projection, cilium .
Protein Description	Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules..
Protein Sequence	MASESVKVVVRCRPMNKRERELSCQSVVTVDSARGQCFIQNPGAADEPPKQFTFDGAYYIEHFTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPCQRGIIPRAFEHVFESVQCAENTKFLVRASYLEIYNEDVHDLLGADTKQRLELKEHPEKGVYVKGLSMHTVHNVAQCERVMETGWKNRAVGYTLMNKDSSRSHSIFTINIEIYAVDERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIKNKPRINEDPKDALLREYQEEIKRLKAILAQQMGPGNLSALLSTQTPPGPVQSEEKLLSPTTVQQDTEAEKQLIREEYEERLARLKADYEAEQESRVRLQEDITAMRNSYDVKLSTLQENLRKEKETEAILKAEVLCKTEVMSRAELASGPEYSPPLQYETAVKPTILSMPDMPPSGKVTKSQAPLAFEEPHGETSRSEFSFESNECSTLEDSATSEAFPGPEEFSNMEFSMAAALTESRYLPEEYLGGQEAAASPLEAERYVQENEPSLEPLRILASLQDPFAEVEAKLARLSSTVAMSDSSQTVVPQIPKQPSSADLLEPSDTKSEADVAVADNVVLGTEPDVNLRVAEEVVSEAETGVWMESEAQVAHVAQVSEEAQPQPLLAMVSVRRESVGVEVAVLTEEELQPVDQQQVLARLQLLEQQVVGGEQAKNKDLREKHKRRKRYADERKKQLVAALQNSDEDGGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLFQQLLEQVQPLIRRDCNYSNLEKIRRESSWDEDNGFWKIPDPIILKTSLPVVPTGTQNKPARKTSAVDSGEPHMQEEDRYKLMLSRSDSENIASNYFRSKRASQILSTDPMKSLTYHNSPPGLNSSLSNNSALPPTQTPEMPQPRPFRLESLDIPFSKAKRKKSKNSFGGEPL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
200	Phosphorylation	WKNRAVGYTLMNKDS CCCCCCEEEEECCCC	7.07	-
201	Phosphorylation	KNRAVGYTLMNKDSS CCCCCEEEEECCCCC	17.38	-
346	Ubiquitination	PRINEDPKDALLREY CCCCCCHHHHHHHHH	68.87	22790023
394	Phosphorylation	QSEEKLLSPTTVQQD CCCCCCCCCCCCCCC	30.54	25293948
424	Phosphorylation	LARLKADYEAEQESR HHHHHCCHHHHHHHH	23.15	20139300
590	Phosphorylation	GGQEAAASPLEAERY CCCCCCCCHHHHHHH	25.87	25293948
961	Phosphorylation	SENIASNYFRSKRAS HHCHHHHHHHCCCHH	9.62	-
978	Phosphorylation	LSTDPMKSLTYHNSP CCCCCCCCCCCCCCC	21.49	25293948
980	Phosphorylation	TDPMKSLTYHNSPPG CCCCCCCCCCCCCCC	29.80	25293948
981	Phosphorylation	DPMKSLTYHNSPPGL CCCCCCCCCCCCCCC	12.33	25293948
984	Phosphorylation	KSLTYHNSPPGLNSS CCCCCCCCCCCCCCC	21.11	25293948
990	Phosphorylation	NSPPGLNSSLSNNSA CCCCCCCCCCCCCCC	37.38	25293948
991	Phosphorylation	SPPGLNSSLSNNSAL CCCCCCCCCCCCCCC	34.44	25293948
993	Phosphorylation	PGLNSSLSNNSALPP CCCCCCCCCCCCCCC	35.59	25293948
996	Phosphorylation	NSSLSNNSALPPTQT CCCCCCCCCCCCCCC	35.12	25293948
1029	Phosphorylation	SKAKRKKSKNSFGGE HHHCCCCCCCCCCCC	39.85	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1029	S	Phosphorylation	Kinase	CAMK2A	Q9UQM7	PSP
1029	S	Phosphorylation	Kinase	CAMK2A	P11798	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KIF17_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KIF17_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KIF17_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KIF17_MOUSE

Related Literatures of Post-Translational Modification