KCTD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KCTD2_HUMAN
• UniProt AC: Q14681
• Protein Name: BTB/POZ domain-containing protein KCTD2
• Gene Name: KCTD2
• Organism: Homo sapiens (Human).
• Sequence Length: 263
• Protein Sequence: MAELQLDPAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVIEPSEKAKILQERGSRM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAELQLDPA ------CCCCCCCHH	26.63	22814378
19	Phosphorylation	GLGGGGGSGVGDGGG CCCCCCCCCCCCCCC	33.31	26074081
33	Phosphorylation	GPVRGPPSPRPAGPT CCCCCCCCCCCCCCC	36.35	25159151
40	Phosphorylation	SPRPAGPTPRGHGRP CCCCCCCCCCCCCCC	25.38	26074081
96	Phosphorylation	TLGREPKSFLCRLCC CCCCCCCCHHHHHHC	33.88	24719451
220	Phosphorylation	LISIGSSYNYGNEDQ HEECCCCCCCCCHHH	17.69	-
222	Phosphorylation	SIGSSYNYGNEDQAE ECCCCCCCCCHHHHH	17.07	-
252	Ubiquitination	IVIEPSEKAKILQER EEECHHHHHHHHHHH	60.35	21906983
254	Ubiquitination	IEPSEKAKILQERGS ECHHHHHHHHHHHHC	55.83	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KCTD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KCTD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KCTD2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CUL3_HUMAN	CUL3	physical	28060381
MYC_HUMAN	MYC	physical	28060381

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.