dbPTM

KCT2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KCT2_MOUSE
UniProt AC	Q8K201
Protein Name	Keratinocyte-associated transmembrane protein 2
Gene Name	Kct2
Organism	Mus musculus (Mouse).
Sequence Length	259
Subcellular Localization	Membrane Single-pass type I membrane protein .
Protein Description
Protein Sequence	MAASALGRMCGAAREKLSPGPGARGLGALARSLVLALLLVPVLCSDRSENPPNNATVSSPVVVTAPGNHTSPSVSQISTTLSPASAEKSGSSSAAPTPTAAPSAPEEEADSNEDPSMEEEDLLALNSSPATGKDTLDNGDYGEPDYDWTTNPRDEEPEDINIAISKESRRFRGFQDSVEVVKLPPPNREDSHFFFHLLIFAFCAAVVYVTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	N-linked_Glycosylation	RSENPPNNATVSSPV CCCCCCCCCEECCCE	42.64	-
68	N-linked_Glycosylation	VVVTAPGNHTSPSVS EEEECCCCCCCCCHH	33.92	-
165	Phosphorylation	EDINIAISKESRRFR CCCCEEEEHHHHCCC	22.73	25521595
223	Phosphorylation	KIFLLVQSRKWRDGL EEEEEEECCCCCCCC	28.48	22817900
233	Ubiquitination	WRDGLCSKTVEYHRL CCCCCCCCCEEHHHC	56.44	-
237	Phosphorylation	LCSKTVEYHRLDQNV CCCCCEEHHHCCCCH	6.47	26032504
250	Phosphorylation	NVNEAMPSLKITNDY CHHHHCCCCCCCCCC	29.25	28066266
252	Ubiquitination	NEAMPSLKITNDYIF HHHCCCCCCCCCCCC	52.39	-
257	Phosphorylation	SLKITNDYIF----- CCCCCCCCCC-----	13.29	21659604

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KCT2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KCT2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KCT2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KCT2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KCT2_MOUSE

Related Literatures of Post-Translational Modification