KCS10_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KCS10_ARATH
• UniProt AC: Q570B4
• Protein Name: 3-ketoacyl-CoA synthase 10 {ECO:0000303|PubMed:18465198}
• Gene Name: FDH {ECO:0000303|PubMed:10559443}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 550
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Description: Contributes to cuticular wax and suberin biosynthesis. Prevents the postgenital fusion of epiderm cells in organs in contact, as well as ectopic pollen hydration and germination. Required during ovules formation. May regulate an epidermis-specific developmental program during gynoecial ontogeny..
• Protein Sequence: MGRSNEQDLLSTEIVNRGIEPSGPNAGSPTFSVRVRRRLPDFLQSVNLKYVKLGYHYLINHAVYLATIPVLVLVFSAEVGSLSREEIWKKLWDYDLATVIGFFGVFVLTACVYFMSRPRSVYLIDFACYKPSDEHKVTKEEFIELARKSGKFDEETLGFKKRILQASGIGDETYVPRSISSSENITTMKEGREEASTVIFGALDELFEKTRVKPKDVGVLVVNCSIFNPTPSLSAMVINHYKMRGNILSYNLGGMGCSAGIIAIDLARDMLQSNPNSYAVVVSTEMVGYNWYVGSDKSMVIPNCFFRMGCSAVMLSNRRRDFRHAKYRLEHIVRTHKAADDRSFRSVYQEEDEQGFKGLKISRDLMEVGGEALKTNITTLGPLVLPFSEQLLFFAALLRRTFSPAAKTSTTTSFSTSATAKTNGIKSSSSDLSKPYIPDYKLAFEHFCFHAASKVVLEELQKNLGLSEENMEASRMTLHRFGNTSSSGIWYELAYMEAKESVRRGDRVWQIAFGSGFKCNSVVWKAMRKVKKPTRNNPWVDCINRYPVPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MGRSNEQDLLS ----CCCCCHHHHHH	38.70	29654922
28	Phosphorylation	PSGPNAGSPTFSVRV CCCCCCCCCCEEEEH	20.53	30291188
173	Phosphorylation	ASGIGDETYVPRSIS HCCCCCCCCCCCCCC	34.26	22074104
174	Phosphorylation	SGIGDETYVPRSISS CCCCCCCCCCCCCCC	13.35	22074104
427	Phosphorylation	AKTNGIKSSSSDLSK CCCCCCCCCCCCCCC	33.27	23111157
428	Phosphorylation	KTNGIKSSSSDLSKP CCCCCCCCCCCCCCC	28.94	25561503
429	Phosphorylation	TNGIKSSSSDLSKPY CCCCCCCCCCCCCCC	34.66	23660473
430	Phosphorylation	NGIKSSSSDLSKPYI CCCCCCCCCCCCCCC	44.51	23111157
436	Phosphorylation	SSDLSKPYIPDYKLA CCCCCCCCCCCHHHH	28.90	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KCS10_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KCS10_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KCS10_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of KCS10_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.