KCNKH_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KCNKH_HUMAN
• UniProt AC: Q96T54
• Protein Name: Potassium channel subfamily K member 17
• Gene Name: KCNK17
• Organism: Homo sapiens (Human).
• Sequence Length: 332
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents..
• Protein Sequence: MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSCCHHSSKEDFKSQSWRQGPDREPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
65	N-linked_Glycosylation	DKWELLQNFTCLDRP HHHHHHHHCCCCCHH	33.88	UniProtKB CARBOHYD
76	Phosphorylation	LDRPALDSLIRDVVQ CCHHHHHHHHHHHHH	26.92	24719451
94	N-linked_Glycosylation	NGASLLSNTTSMGRW CCHHHHCCCCCCCCE	47.55	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KCNKH_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KCNKH_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KCNKH_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of KCNKH_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.