KCNH7_RAT - dbPTM
KCNH7_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KCNH7_RAT
UniProt AC O54852
Protein Name Potassium voltage-gated channel subfamily H member 7
Gene Name Kcnh7
Organism Rattus norvegicus (Rat).
Sequence Length 1195
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly..
Protein Sequence MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEDNAASPERVNPILPVKSVNRKLFGFKFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFNVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAVHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKSQSINDSEGDTCKLRRRRLSFESEGDKDFSKENSANDADDSTDTIRRYQSSKKHFEEKKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKASRHHGEEAAPPSGRIHTDKRSHSCKDITDTHSWEREHARAQPEECSPSGLQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGKRLNTASEDNLTSLLKQDSDASSELDPRQRKSYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
174PhosphorylationVLTYRKQSLPQEDPD
EEEECCCCCCCCCCC		45.0822673903
226PhosphorylationLIQPSQCSPLVNISG
HCCHHHCCCCEECCC		17.40-
238PhosphorylationISGPLDHSSPKRQWD
CCCCCCCCCCHHHHH		48.2625403869
239PhosphorylationSGPLDHSSPKRQWDR
CCCCCCCCCHHHHHH		30.9025403869
274PhosphorylationLCSIRRASSVHDIEG
HHHHHCCCCCCCCCC		30.95-
275PhosphorylationCSIRRASSVHDIEGF
HHHHCCCCCCCCCCC		23.61-
317PhosphorylationIKSSLLGSTSDSNLN
HHHHHCCCCCCCCCC		25.3822673903
318PhosphorylationKSSLLGSTSDSNLNK
HHHHCCCCCCCCCCC		34.4522673903
319PhosphorylationSSLLGSTSDSNLNKY
HHHCCCCCCCCCCCC		40.5122673903
321PhosphorylationLLGSTSDSNLNKYST
HCCCCCCCCCCCCCC		42.8822673903
326PhosphorylationSDSNLNKYSTINKIP
CCCCCCCCCCCCCCC		15.2425575281
327PhosphorylationDSNLNKYSTINKIPQ
CCCCCCCCCCCCCCE		25.1525575281
328PhosphorylationSNLNKYSTINKIPQL
CCCCCCCCCCCCCEE		26.0225575281
343UbiquitinationTLNFSDVKTEKKNTS
EECHHHCCCCCCCCC		56.83-
350PhosphorylationKTEKKNTSPPSSDKT
CCCCCCCCCCCCCCC		44.1825403869
600N-linked_GlycosylationTQIGKRYNDSDSSSG
CHHHHHCCCCCCCCC		46.47-
614PhosphorylationGPSIKDKYVTALYFT
CCCHHHCCEEEEEEE		17.1116641100
616PhosphorylationSIKDKYVTALYFTFS
CHHHCCEEEEEEEHH		14.0916641100
621PhosphorylationYVTALYFTFSSLTSV
CEEEEEEEHHCCCCC		14.7316641100
623PhosphorylationTALYFTFSSLTSVGF
EEEEEEHHCCCCCCC		22.7516641100
624PhosphorylationALYFTFSSLTSVGFG
EEEEEHHCCCCCCCC		31.3216641100
872PhosphorylationLRHESAKSQSINDSE
CCCHHHHCCCCCCCC		28.95-
891PhosphorylationKLRRRRLSFESEGDK
HHHHHHHHCCCCCCC		25.7525403869
894PhosphorylationRRRLSFESEGDKDFS
HHHHHCCCCCCCCCC		44.8922673903
1169PhosphorylationLHPIRHPSLPDSSLS
CCCCCCCCCCCCCCC		46.5425403869
1188PhosphorylationLGLHRHVSDPGLPGK
EEECCCCCCCCCCCC		31.7825403869
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KCNH7_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KCNH7_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KCNH7_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of KCNH7_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KCNH7_RAT

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Related Literatures of Post-Translational Modification

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