dbPTM

KCD20_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KCD20_MOUSE
UniProt AC	Q8CDD8
Protein Name	BTB/POZ domain-containing protein KCTD20
Gene Name	Kctd20
Organism	Mus musculus (Mouse).
Sequence Length	419
Subcellular Localization	Cytoplasm . Colocalizes with BTBD10 in filamentous structures.
Protein Description	Promotes the phosphorylation of AKT family members..
Protein Sequence	MNVHQGSDGDWSLQPELSCLGDEALAATQEKEGSSLVSSGLHSVTYPLAARSEDLALDYASQPASLPHPHIMPLPEDNKGSCFQSGSKRSHEPFIVPERFGNSGLGFGGGAHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYVIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIIMHHPPQVDELDRLNAPLSQMAPNDFQD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	GDEALAATQEKEGSS CHHHHHHHHHHHCCC	31.49	28576409
164	Phosphorylation	RPNEKGEYVIAEGIS CCCCCCCEEEECCCE	13.06	-
171	Phosphorylation	YVIAEGISATVFRTV EEEECCCEEEHHHHH	28.83	-
374	Phosphorylation	FQCVRSKSLTNLVAA EEEEECCCHHHHHHC	41.49	19060867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KCD20_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KCD20_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KCD20_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KCD20_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KCD20_MOUSE

Related Literatures of Post-Translational Modification