dbPTM

KC1A_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KC1A_CAEEL
UniProt AC	P42168
Protein Name	Casein kinase I isoform alpha
Gene Name	kin-19
Organism	Caenorhabditis elegans.
Sequence Length	341
Subcellular Localization
Protein Description
Protein Sequence	MAGVMSVKDFIVATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAQQSQSSGVPGTNTTTQGATVPSAGVPAGVAPGGTTPQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
293	Phosphorylation	TLNHQYDYTFDWTML HCCCCCCCCEEHHHH	12.36	27067626
315	Phosphorylation	QSSGVPGTNTTTQGA HHCCCCCCCCCCCCC	24.26	30078680
317	Phosphorylation	SGVPGTNTTTQGATV CCCCCCCCCCCCCCC	30.93	30078680
318	Phosphorylation	GVPGTNTTTQGATVP CCCCCCCCCCCCCCC	21.13	30078680
319	Phosphorylation	VPGTNTTTQGATVPS CCCCCCCCCCCCCCC	23.98	30078680
323	Phosphorylation	NTTTQGATVPSAGVP CCCCCCCCCCCCCCC	39.51	30078680
326	Phosphorylation	TQGATVPSAGVPAGV CCCCCCCCCCCCCCC	33.06	30078680
338	Phosphorylation	AGVAPGGTTPQ---- CCCCCCCCCCC----	41.01	28854356
339	Phosphorylation	GVAPGGTTPQ----- CCCCCCCCCC-----	23.98	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KC1A_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KC1A_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KC1A_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KC1A_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KC1A_CAEEL

Related Literatures of Post-Translational Modification