KBTB3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KBTB3_HUMAN
• UniProt AC: Q8NAB2
• Protein Name: Kelch repeat and BTB domain-containing protein 3
• Gene Name: KBTBD3
• Organism: Homo sapiens (Human).
• Sequence Length: 608
• Protein Sequence: MDNSYAFNQRSTCNGIPSEKKNNFLVSEDHGQKILSVLQNFREQNVFYDFKIIMKDEIIPCHRCVLAACSDFFRAMFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKTKITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSINLVNCLQLLSISDSYGSTSLFDHALHFVQHHFSLLFKSSDFLEMNFGVLQKCLESDELNVPEEEMVLKVVLSWTKHNLESRQKYLPHLIEKVRLHQLSEETLQDCLFNEESLLKSTNCFDIIMDAIKCVQGSGGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKSDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRTVRLHIAESYHDATDQTWCYCPVKNDFFLVSTMKTPRTMHTSVMALDRLFVIGGKTRGSRDIKSLLDVESYNPLSKEWISVSPLPRGIYYPEASTCQNVIYVLGSEVEITDAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSNRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWFSNLCA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
92	Phosphorylation	DDGSVTITNLSSKAV CCCCEEEEECCHHHH	22.27	-
101	Ubiquitination	LSSKAVKAFLDYAYT CCHHHHHHHHHHHHH	12.02	-
256	Phosphorylation	DCLFNEESLLKSTNC HHHCCHHHHHHCCCH	32.59	24719451
390	Phosphorylation	STMKTPRTMHTSVMA EECCCCCCCCHHHHH	17.95	29759185
393	Phosphorylation	KTPRTMHTSVMALDR CCCCCCCHHHHHCCE	16.52	29759185
394	Phosphorylation	TPRTMHTSVMALDRL CCCCCCHHHHHCCEE	8.67	29759185
415	Ubiquitination	TRGSRDIKSLLDVES CCCCCCHHHHHCHHH	39.06	-
419	Ubiquitination	RDIKSLLDVESYNPL CCHHHHHCHHHCCCC	47.64	-
428	Ubiquitination	ESYNPLSKEWISVSP HHCCCCCCCEEECCC	65.83	2190698
432	Ubiquitination	PLSKEWISVSPLPRG CCCCCEEECCCCCCC	20.02	21906983
434	Phosphorylation	SKEWISVSPLPRGIY CCCEEECCCCCCCCC	17.58	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KBTB3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KBTB3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KBTB3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of KBTB3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.