| UniProt ID | K2C4_MOUSE | |
|---|---|---|
| UniProt AC | P07744 | |
| Protein Name | Keratin, type II cytoskeletal 4 | |
| Gene Name | Krt4 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 525 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MIARQSSVRGASRGFSSGSAIAGGVKRVAFSSGSMSGGAGRCSSGGFGSRSLYNLGGHKSISMSVAGSCQGGGYGGAGGFGVGGYGAGFGAGGFGGGFGGSFNGRGGPGFPVCPAGGIQEVTINQSLLTPLQVEIDPEIQKIRTAEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQTTTTSPKSLDPFFETYINALRKNLDTLSNDKGRLQSELKMMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYMIKVELEAKMESLKDEINFTRVLYEAELAQMQTHVSDTSVVLSMDNNRNLDLDGIIAEVRAQYEDIARKSKAEVESWYQIKVQQLQMSADQHGDSLKTTKNEISELNRMIQRLRAEIENIKKQSQTLQASVADAEQRGELALKDAYSKRAELETALQKAKEDLARLLRDYQALMNVKLALDVEIATYRKLLEGEECRMSGECKSAVSISVVGGSASIGGSGLGLGSGFCSGSGSGSGFGFGGGIYGGSGSKITSSATITKRSPR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 13 | Methylation | SSVRGASRGFSSGSA CCCCCCCCCCCCCCH | 50.03 | 24129315 | |
| 19 | Phosphorylation | SRGFSSGSAIAGGVK CCCCCCCCHHHCCCE | 20.60 | 19367708 | |
| 34 | Phosphorylation | RVAFSSGSMSGGAGR EEEECCCCCCCCCCC | 16.24 | 19367708 | |
| 51 | Phosphorylation | SGGFGSRSLYNLGGH CCCCCCCCCEECCCC | 36.58 | 22817900 | |
| 152 | Phosphorylation | AEREQIKTLNNKFAS HHHHHHHHHHHHHHH | 36.03 | 29899451 | |
| 156 | Ubiquitination | QIKTLNNKFASFIDK HHHHHHHHHHHHHHH | 41.03 | - | |
| 159 | Phosphorylation | TLNNKFASFIDKVRF HHHHHHHHHHHHHHH | 26.35 | 22817900 | |
| 163 | Ubiquitination | KFASFIDKVRFLEQQ HHHHHHHHHHHHHHH | 30.41 | 27667366 | |
| 450 | Ubiquitination | VEIATYRKLLEGEEC HHHHHHHHHHCCCCC | 47.19 | 27667366 | |
| 457 | S-nitrosocysteine | KLLEGEECRMSGECK HHHCCCCCCCCCCCC | 3.73 | - | |
| 457 | S-nitrosylation | KLLEGEECRMSGECK HHHCCCCCCCCCCCC | 3.73 | 21278135 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of K2C4_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of K2C4_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of K2C4_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of K2C4_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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