K1H2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: K1H2_HUMAN
• UniProt AC: Q14532
• Protein Name: Keratin, type I cuticular Ha2
• Gene Name: KRT32
• Organism: Homo sapiens (Human).
• Sequence Length: 448
• Protein Sequence: MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTCVPSPCVPRTVCVPRTVGMPCSPCPQGRY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MTSSCCVTNN -----CCCCCCCCCC	21.78	20860994
4	Phosphorylation	----MTSSCCVTNNL ----CCCCCCCCCCH	11.45	20860994
66	Phosphorylation	ASCLSKTYLSSSCQA HHHCCHHHHCHHCHH	14.34	30576142
68	Phosphorylation	CLSKTYLSSSCQAAS HCCHHHHCHHCHHHC	15.14	30576142
78	Phosphorylation	CQAASGISGSMGPGS CHHHCCCCCCCCCCC	28.48	30576142
109	Phosphorylation	FLNDRLASYLTRVRQ HHHHHHHHHHHHHHH	25.85	23403867
110	Phosphorylation	LNDRLASYLTRVRQL HHHHHHHHHHHHHHH	13.39	23403867
112	Phosphorylation	DRLASYLTRVRQLEQ HHHHHHHHHHHHHHH	20.91	23403867
113	Dimethylation	RLASYLTRVRQLEQE HHHHHHHHHHHHHHH	21.01	-
113	Methylation	RLASYLTRVRQLEQE HHHHHHHHHHHHHHH	21.01	4294443
149	Phosphorylation	DYQSHFRTIEELQQK CHHHHCCHHHHHHHH	31.62	-
339	Phosphorylation	LRDSLENTLTESEAR HHHHHHHHCCHHHHH	26.19	19690332
341	Phosphorylation	DSLENTLTESEARYS HHHHHHCCHHHHHHH	35.11	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of K1H2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of K1H2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of K1H2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of K1H2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.