K1C9_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: K1C9_MOUSE
• UniProt AC: Q6RHW0
• Protein Name: Keratin, type I cytoskeletal 9
• Gene Name: Krt9 {ECO:0000312|MGI:MGI:96696}
• Organism: Mus musculus (Mouse).
• Sequence Length: 743
• Protein Description: May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly (By similarity). Plays an essential role in the correct development of sperm..
• Protein Sequence: MSCRQSSSSFWSSSSSCGGGGGRGGSGGSMRSSFSRSSRAGGGGGGRFNSSSGFSGGGFSACGGGGGGSFGSSYGGGYGGGFSTGSYSGMFGGGSGGGFGGGSGGGFGGGSGGGFGGGSGGGEGGILNTNEKIVMQNLNSRLASYMEKVLELEESNTAMEKQIQDWYSKRGPKVFQKDNTHYYDTIEDLKDRIVDLTVRNNKTLVDIDNTRMTMDDFRVKLEMEQSLRQGVEGDINGLKKVLDDLVMAKSDLEILLDSLEDEKNALTKNHKEEMSQLTGQNDGDVNVEINVAPSTDLTRVLNDMREEYEQLISKNRQDIEQHYESKMTQIEQQMTNSGQEMESNMKQVSQLQHTIQELNVELQTQLTTKSALEKALEDTKNRYCGQLQQIQEQISELEAQLAEIRAETECQSQEYSILLSIKTRLEKEIETYRELLEGGQQDFESSGAGQIGFGSGKGRQRGSGGSYGGGSGGSYGGGSGGSYGGGSGGSYGGGSGGSYGGGSGGSHGGKSGGSHGGGSGGSYGGESGGSHGGGSGGSYGGGSGGSHGGKSGGGYGGGSSSGGGSGGSYGGGSGGSHGGGSGGSYGGGSGGSHGGKSGGGYGGGSSSGGGSGGSYGGGSGGSHGGKSGGSYGGGSGGSYGGGSGGSHGGKSGGGYGGGSSSGGGSGGSYGGGSGGSHGGKSGGSYGGGSSSGGGSGGSYGGGSGSGGGSGGSYGGGNRRPSQSQSSSKSADCDDDSQEHKMRY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	SSSFWSSSSSCGGGG CCCCCCCCCCCCCCC	22.28	-
16	Phosphorylation	SFWSSSSSCGGGGGR CCCCCCCCCCCCCCC	20.80	-
26	Phosphorylation	GGGGRGGSGGSMRSS CCCCCCCCCCCCCCC	42.69	22817900
29	Phosphorylation	GRGGSGGSMRSSFSR CCCCCCCCCCCCCCC	17.97	22817900
32	Phosphorylation	GSGGSMRSSFSRSSR CCCCCCCCCCCCCCC	27.39	22817900
35	Phosphorylation	GSMRSSFSRSSRAGG CCCCCCCCCCCCCCC	32.95	22817900
37	Phosphorylation	MRSSFSRSSRAGGGG CCCCCCCCCCCCCCC	23.99	22817900
55	Phosphorylation	FNSSSGFSGGGFSAC CCCCCCCCCCCCCCC	39.80	-
155	Phosphorylation	KVLELEESNTAMEKQ HHHHHHHHCHHHHHH	30.06	-
218	Methylation	RMTMDDFRVKLEMEQ CCCHHHHHHHHHHHH	31.49	30987723
335	Phosphorylation	TQIEQQMTNSGQEME HHHHHHHHHHHHHHH	21.47	-
337	Phosphorylation	IEQQMTNSGQEMESN HHHHHHHHHHHHHHH	32.46	-
471	Phosphorylation	GGSYGGGSGGSYGGG CCCCCCCCCCCCCCC	43.16	-
474	Phosphorylation	YGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	-
475	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
479	Phosphorylation	GGSYGGGSGGSYGGG CCCCCCCCCCCCCCC	43.16	-
482	Phosphorylation	YGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	-
483	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
487	Phosphorylation	GGSYGGGSGGSYGGG CCCCCCCCCCCCCCC	43.16	20139300
490	Phosphorylation	YGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	-
491	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
495	Phosphorylation	GGSYGGGSGGSYGGG CCCCCCCCCCCCCCC	43.16	20139300
498	Phosphorylation	YGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	20139300
499	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	20139300
503	Phosphorylation	GGSYGGGSGGSHGGK CCCCCCCCCCCCCCC	43.16	20139300
506	Phosphorylation	YGGGSGGSHGGKSGG CCCCCCCCCCCCCCC	23.60	20139300
511	Phosphorylation	GGSHGGKSGGSHGGG CCCCCCCCCCCCCCC	52.22	-
538	Phosphorylation	HGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	-
539	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
543	Phosphorylation	GGSYGGGSGGSHGGK CCCCCCCCCCCCCCC	43.16	-
546	Phosphorylation	YGGGSGGSHGGKSGG CCCCCCCCCCCCCCC	23.60	-
569	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
584	Phosphorylation	HGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	-
585	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
589	Phosphorylation	GGSYGGGSGGSHGGK CCCCCCCCCCCCCCC	43.16	-
592	Phosphorylation	YGGGSGGSHGGKSGG CCCCCCCCCCCCCCC	23.60	-
615	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
619	Phosphorylation	GGSYGGGSGGSHGGK CCCCCCCCCCCCCCC	43.16	-
622	Phosphorylation	YGGGSGGSHGGKSGG CCCCCCCCCCCCCCC	23.60	-
627	Phosphorylation	GGSHGGKSGGSYGGG CCCCCCCCCCCCCCC	52.22	20139300
635	Phosphorylation	GGSYGGGSGGSYGGG CCCCCCCCCCCCCCC	43.16	20139300
638	Phosphorylation	YGGGSGGSYGGGSGG CCCCCCCCCCCCCCC	24.91	20139300
639	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	20139300
643	Phosphorylation	GGSYGGGSGGSHGGK CCCCCCCCCCCCCCC	43.16	20139300
646	Phosphorylation	YGGGSGGSHGGKSGG CCCCCCCCCCCCCCC	23.60	20139300
669	Phosphorylation	GGGSGGSYGGGSGGS CCCCCCCCCCCCCCC	24.06	-
673	Phosphorylation	GGSYGGGSGGSHGGK CCCCCCCCCCCCCCC	43.16	-
676	Phosphorylation	YGGGSGGSHGGKSGG CCCCCCCCCCCCCCC	23.60	-
681	Phosphorylation	GGSHGGKSGGSYGGG CCCCCCCCCCCCCCC	52.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of K1C9_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of K1C9_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of K1C9_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of K1C9_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.