dbPTM

K1C42_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	K1C42_MOUSE
UniProt AC	Q6IFX2
Protein Name	Keratin, type I cytoskeletal 42
Gene Name	Krt42 {ECO:0000312\|MGI:MGI:1915489}
Organism	Mus musculus (Mouse).
Sequence Length	452
Subcellular Localization	Cytoplasm .
Protein Description
Protein Sequence	MASTTSVRQFSTSGSVKGLCAPGMGFSRMSSVRVGGACRAPSLLGGGSCGNMSVTSSRFSAGLGGGYGGGYTCSLGGGFGSSFGVSDALLGGSEKETMQNLNDRLATYLDRVRALEEANADLEVKIREWYKKQGPGPARDYSPYFKTIEDLRNKILAATIDNASIVLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNTEALQSSRTEITELRRSVQNLEIELQSQLSMKASLENSLAETEARYGAQLAQLQGLISSVEQQLCELRCDMERQNHEYQVLLDVKTRLEQEIATYRRLLEGEDAHLATQYSSSLASQPSREGMVTSRQVRTIVEEVQDGKVVSSREQVHRSTH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	RQFSTSGSVKGLCAP EEEECCCCCCCEECC	22.03	22006019
192	Phosphorylation	TELNLRMSVEADING HHHHHCEEEEECHHH	15.46	-
222	Acetylation	EMQIESLKEELAYLR HHHHHHHHHHHHHHH	59.42	22902405
229	Dimethylation	KEELAYLRKNHEEEM HHHHHHHHHCCHHHH	25.67	-
229	Methylation	KEELAYLRKNHEEEM HHHHHHHHHCCHHHH	25.67	18966011
298	Phosphorylation	ELNREVATNTEALQS HHHHHHHHCHHHHHH	48.09	29899451
300	Phosphorylation	NREVATNTEALQSSR HHHHHHCHHHHHHCH	20.48	-
306	Phosphorylation	NTEALQSSRTEITEL CHHHHHHCHHHHHHH	30.20	-
311	Phosphorylation	QSSRTEITELRRSVQ HHCHHHHHHHHHHHH	23.80	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of K1C42_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of K1C42_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of K1C42_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of K1C42_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of K1C42_MOUSE

Related Literatures of Post-Translational Modification