dbPTM

K1C26_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	K1C26_HUMAN
UniProt AC	Q7Z3Y9
Protein Name	Keratin, type I cytoskeletal 26
Gene Name	KRT26 {ECO:0000312\|EMBL:AAI32952.1}
Organism	Homo sapiens (Human).
Sequence Length	468
Subcellular Localization
Protein Description
Protein Sequence	MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGWYEKCEPGSSREHDHDYSRYFSVIEDLKRQIISATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSFRLSGGS ------CCEECCCCC	21.05	24719451
6	Phosphorylation	--MSFRLSGGSRRIC --CCEECCCCCCEEE	36.53	-
119	Phosphorylation	EQKIKGWYEKCEPGS HHHHHHHHHHCCCCC	17.74	23836654
201	Phosphorylation	RRVLDELTLCTTDLE HHHHHHHHCCCCCCC	20.10	-
272	Ubiquitination	DLAEQNRKDAEAWFN HHHHHHHHHHHHHHH	69.69	22817900
401	Phosphorylation	EERKSKSTCYKSKGY CCCCCCCCCCCCCCC	24.48	-
428	Phosphorylation	TEETIVKTVVEELDQ CHHHHHHHHHHHHHH	20.91	20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of K1C26_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of K1C26_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of K1C26_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of K1C26_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of K1C26_HUMAN

Related Literatures of Post-Translational Modification