K1C25_MOUSE - dbPTM
K1C25_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID K1C25_MOUSE
UniProt AC Q8VCW2
Protein Name Keratin, type I cytoskeletal 25
Gene Name Krt25 {ECO:0000312|EMBL:AAH18391.1, ECO:0000312|MGI:MGI:1918060}
Organism Mus musculus (Mouse).
Sequence Length 446
Subcellular Localization Cytoplasm .
Protein Description Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). [PubMed: 14996088]
Protein Sequence MSLRLSSGSRRSYARPSTGSLRGASFGAGNACGVAGIGSGFSCAFGGSSTGGNTGVANSCAGFTVNEGGLLSGNEKVTMQNLNDRLASYLDNVQALQEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIITSTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEELTYLKKNHKEEMQALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFQEKSASLQQQITEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETEGNYCTQLAQIQAQISALEEQLHQVRTETEGQKLEYEQLLNVKAHLEKEIETYCLLIGGDEGACKSSSYKSKDYGSGNAGNQIKDPVKAIVVKKVLEEVDQRSKILTTRLHSLEEKSQSN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
245PhosphorylationAAPGVDLTVLLNNMR
CCCCCCHHHHHHHHH
12.4917203969
402PhosphorylationYKSKDYGSGNAGNQI
CCCCCCCCCCCCCCC
23.7323375375
438PhosphorylationILTTRLHSLEEKSQS
HHHHHHHHHHHHHHC
41.91-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of K1C25_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of K1C25_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of K1C25_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of K1C25_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of K1C25_MOUSE

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Related Literatures of Post-Translational Modification

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