| UniProt ID | K1C16_MOUSE | |
|---|---|---|
| UniProt AC | Q9Z2K1 | |
| Protein Name | Keratin, type I cytoskeletal 16 | |
| Gene Name | Krt16 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 469 | |
| Subcellular Localization | ||
| Protein Description | Epidermis-specific type I keratin that plays a key role in skin. [PubMed: 22336941] | |
| Protein Sequence | MATCSRQFTSSSSMKGSCGIGGGSSRMSSILAGGSCRAPSTCGGMSVTSSRFSSGGVCGIGGGYGGSFSSSSFGGGLGSGFGGRFDGFGGGFGAGLGGGLGGGIGDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLEVKIRDWYQRQRPTEIKDYSPYFKTIEDLKSKIIIATQENAQFTLQIDNARLAADDFRTKYENELFLRQSVEGDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDVEAWFLRKTEELNKEVASNSDLIQSNRSEVAELRRVFQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLISSVEEQLAQLRCEMEQQSQEYNILLDVKTRLEQEIATYRRLLDGENIHSSSQHSSGQSYSSREVFSSSSRQPRSILKEQGSTSFSQSQSQSSRD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Phosphorylation | TCSRQFTSSSSMKGS CCCCCCCCCCCCCCC | 29.52 | - | |
| 11 | Phosphorylation | CSRQFTSSSSMKGSC CCCCCCCCCCCCCCC | 24.31 | 21183079 | |
| 12 | Phosphorylation | SRQFTSSSSMKGSCG CCCCCCCCCCCCCCC | 33.93 | 19060867 | |
| 13 | Phosphorylation | RQFTSSSSMKGSCGI CCCCCCCCCCCCCCC | 26.85 | 22817900 | |
| 17 | Phosphorylation | SSSSMKGSCGIGGGS CCCCCCCCCCCCCCC | 12.03 | 21082442 | |
| 24 | Phosphorylation | SCGIGGGSSRMSSIL CCCCCCCCHHHCHHH | 20.32 | 19367708 | |
| 28 | Phosphorylation | GGGSSRMSSILAGGS CCCCHHHCHHHCCCC | 17.08 | 22817900 | |
| 29 | Phosphorylation | GGSSRMSSILAGGSC CCCHHHCHHHCCCCC | 16.57 | 19367708 | |
| 35 | Phosphorylation | SSILAGGSCRAPSTC CHHHCCCCCCCCCCC | 10.26 | 19367708 | |
| 51 | Methylation | GMSVTSSRFSSGGVC CCEECCCCCCCCCCC | 34.92 | - | |
| 356 | Phosphorylation | MKASLENSLEETKGR HHHHHHHHHHHHCCC | 27.99 | - | |
| 435 | Phosphorylation | HSSGQSYSSREVFSS CCCCCCCCCHHHHCC | 28.32 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of K1C16_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of K1C16_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of K1C16_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of K1C16_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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