| UniProt ID | K1C15_MOUSE | |
|---|---|---|
| UniProt AC | Q61414 | |
| Protein Name | Keratin, type I cytoskeletal 15 | |
| Gene Name | Krt15 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 452 | |
| Subcellular Localization | ||
| Protein Description | In the absence of KRT14, makes a bona fide, but ultrastructurally distinct keratin filament network with KRT5.. | |
| Protein Sequence | MATTFLQTSSTFGGSSTRGASLRAGGGSFGGGSLYGGGGSRSISASSARFVSSGAGGGFGGGMSCGFGGGFGGGFGGGFGGGFGDFGGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELEVKIRDWYQKQSPASPDRDYSHYFKTMEEIRDKILAATIDNSRVVLEIDNARLAADDFRLKYENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTLQGLEIELQSQLSMKAGLENSLAEVECRYATQLQQIQGVITGLETQLSELRCEMEAQNQEYNMLLDIKTRLEQEIATYRNLLEGQDAKMAGIGVREGSSGGGGSSSSSSNFHISVEESVDGKVVSSRKREI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 15 | Phosphorylation | TSSTFGGSSTRGASL ECCCCCCCCCCCEEE | 28.99 | - | |
| 16 | Phosphorylation | SSTFGGSSTRGASLR CCCCCCCCCCCEEEE | 25.96 | - | |
| 28 | Phosphorylation | SLRAGGGSFGGGSLY EEEECCCCCCCCCCC | 24.80 | 22817900 | |
| 33 | Phosphorylation | GGSFGGGSLYGGGGS CCCCCCCCCCCCCCC | 22.99 | 17203969 | |
| 35 | Phosphorylation | SFGGGSLYGGGGSRS CCCCCCCCCCCCCCC | 18.54 | 17203969 | |
| 47 | Phosphorylation | SRSISASSARFVSSG CCCCCHHHCEEECCC | 24.15 | - | |
| 111 | Phosphorylation | NLNDRLASYLDKVRA CHHHHHHHHHHHHHH | 30.71 | - | |
| 124 | Phosphorylation | RALEQANTELEVKIR HHHHHHCCEEEHHHH | 44.99 | - | |
| 138 | Phosphorylation | RDWYQKQSPASPDRD HHHHHHCCCCCCCCC | 29.48 | 19060867 | |
| 141 | Phosphorylation | YQKQSPASPDRDYSH HHHCCCCCCCCCCHH | 30.62 | 21082442 | |
| 294 | Phosphorylation | EAWFFSKTEELNKEV HHHHEECHHHHHHHH | 33.23 | - | |
| 316 | Phosphorylation | QTSKTEITDLRRTLQ CCCCHHHHHHHHHHH | 23.81 | - | |
| 331 | Phosphorylation | GLEIELQSQLSMKAG HHHHHHHHHHHHHHC | 45.79 | - | |
| 425 | Phosphorylation | GSSGGGGSSSSSSNF CCCCCCCCCCCCCCE | 30.26 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of K1C15_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of K1C15_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of K1C15_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of K1C15_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Protein phosphorylation and expression profiling by Yin-yangmultidimensional liquid chromatography (Yin-yang MDLC) massspectrometry."; Dai J., Jin W.-H., Sheng Q.-H., Shieh C.-H., Wu J.-R., Zeng R.; J. Proteome Res. 6:250-262(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-35, AND MASSSPECTROMETRY. | |
