| UniProt ID | K154L_HUMAN | |
|---|---|---|
| UniProt AC | Q6ZVL6 | |
| Protein Name | UPF0606 protein KIAA1549L | |
| Gene Name | KIAA1549L | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1849 | |
| Subcellular Localization |
Membrane Single-pass membrane protein . |
|
| Protein Description | ||
| Protein Sequence | MDHTASQNAQDLIGIPHLGVSGSSTKWHSELSPTEGPHSAGSSTPGFLSPMAELSHPSPPPPALGSLLQLPDGSPSWSMLEVASGPASTQQIKAGVPGRVHNGVSLPTFKNTETATHEAEPPLFQTAESGAIEMTSRKLASATANDSANPLHLSAAPENSRGPALSAEHTSSLVPSLHITTLGQEQAILSGAVPASPSTGTADFPSILTFLQPTENHASPSPVPEMPTLPAEGSDGSPPATRDLLLSSKVPNLLSTSWTFPRWKKDSVTAILGKNEEANVTIPLQAFPRKEVLSLHTVNGFVSDFSTGSVSSPIITAPRTNPLPSGPPLPSILSIQATQTVFPSLGFSSTKPEAYAAAVDHSGLPASASKQVRASPSSMDVYDSLTIGDMKKPATTDVFWSSLSAETGSLSTESIISGLQQQTNYDLNGHTISTTSWETHLAPTAPPNGLTSAADAIKSQDFKDTAGHSVTAEGFSIQDLVLGTSIEQPVQQSDMTMVGSHIDLWPTSNNNHSRDFQTAEVAYYSPTTRHSVSHPQLQLPNQPAHPLLLTSPGPTSTGSLQEMLSDGTDTGSEISSDINSSPERNASTPFQNILGYHSAAESSISTSVFPRTSSRVLRASQHPKKWTADTVSSKVQPTAAAAVTLFLRKSSPPALSAALVAKGTSSSPLAVASGPAKSSSMTTLAKNVTNKAASGPKRTPGAVHTAFPFTPTYMYARTGHTTSTHTAMQGNMDTASGLLSTTYLPRKPQAMHTGLPNPTNLEMPRASTPRPLTVTAALTSITASVKATRLPPLRAENTDAVLPAASAAVVTTGKMASNLECQMSSKLLVKTVLFLTQRRVQISESLKFSIAKGLTQALRKAFHQNDVSAHVDILEYSHNVTVGYYATKGKLVYLPAVVIEMLGVYGVSNVTADLKQHTPHLQSVAVLASPWNPQPAGYFQLKTVLQFVSQADNIQSCKFAQTMEQRLQKAFQDAERKVLNTKSNLTIQIVSTSNASQAVTLVYVVGNQSTFLNGTVASSLLSQLSAELVGFYLTYPPLTIAEPLEYPNLDISETTRDYWVITVLQGVDNSLVGLHNQSFARVMEQRLAQLFMMSQQQGRRFKRATTLGSYTVQMVKMQRVPGPKDPAELTYYTLYNGKPLLGTAAAKILSTIDSQRMALTLHHVVLLQADPVVKNPPNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMINLPQRAKPVQGFDYAKQHLGQQGADEEVIPVTQETVVLPLPIRDAPQERDVAQDGSTIKTAKSTETRKSRSPSENGSVISNESGKPSSGRRSPQNVMAQQKVTKEEARKRNVPASDEEEGAVLFDNSSKVAAEPFDTSSGSVQLIAIKPTALPMVPPTSDRSQESSAVLNGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPAVETSKGLTERKKMYEKAPKEMEHVLDPDSELCAPFTESKNRQQMKNSVYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNIDRVPEPRGYSRSRQVKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHAGQSRHQEAYGSAQHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKTRMAESTGPEPAQLHDSASFTQMSRGPVSVTQLDQSALNYSGNTVPAVFAIPAANRPGFTGYFIPTPPSSYRNQAWMSYAGENELPSQWADSVPLPGYIEAYPRSRYPQSSPSRLPRQYSQPANLHPSLEQAPAPSTAASQQSLAENDPSDAPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | O-linked_Glycosylation | ----MDHTASQNAQD ----CCCCCCCCHHH | OGP | ||
| 21 | Phosphorylation | GIPHLGVSGSSTKWH CCCCCCCCCCCCCCC | 23879269 | ||
| 23 | Phosphorylation | PHLGVSGSSTKWHSE CCCCCCCCCCCCCCC | 23879269 | ||
| 24 | Phosphorylation | HLGVSGSSTKWHSEL CCCCCCCCCCCCCCC | 23879269 | ||
| 105 | O-linked_Glycosylation | GRVHNGVSLPTFKNT CCCCCCCCCCCCCCC | 55832881 | ||
| 247 | Phosphorylation | ATRDLLLSSKVPNLL HHHHHHHCCCCCCCC | 21712546 | ||
| 248 | Phosphorylation | TRDLLLSSKVPNLLS HHHHHHCCCCCCCCC | 21712546 | ||
| 267 | Phosphorylation | FPRWKKDSVTAILGK CCCCCCCCEEEEECC | - | ||
| 281 | Phosphorylation | KNEEANVTIPLQAFP CCCCCCEEEECCCCC | - | ||
| 344 | Phosphorylation | ATQTVFPSLGFSSTK EECCCCCCCCCCCCC | - | ||
| 598 | Phosphorylation | QNILGYHSAAESSIS HHHHCHHHHHCCCCC | - | ||
| 602 | Phosphorylation | GYHSAAESSISTSVF CHHHHHCCCCCCCCC | - | ||
| 605 | Phosphorylation | SAAESSISTSVFPRT HHHCCCCCCCCCCCC | - | ||
| 632 | Phosphorylation | KWTADTVSSKVQPTA CCCCCCCCCCCCHHH | - | ||
| 633 | Phosphorylation | WTADTVSSKVQPTAA CCCCCCCCCCCHHHH | - | ||
| 638 | O-linked_Glycosylation | VSSKVQPTAAAAVTL CCCCCCHHHHHHHHH | 46217269 | ||
| 638 | Phosphorylation | VSSKVQPTAAAAVTL CCCCCCHHHHHHHHH | - | ||
| 644 | O-linked_Glycosylation | PTAAAAVTLFLRKSS HHHHHHHHHHHHHCC | 46217275 | ||
| 644 | Phosphorylation | PTAAAAVTLFLRKSS HHHHHHHHHHHHHCC | - | ||
| 650 | O-linked_Glycosylation | VTLFLRKSSPPALSA HHHHHHHCCCCHHHH | 55411979 | ||
| 650 | Phosphorylation | VTLFLRKSSPPALSA HHHHHHHCCCCHHHH | - | ||
| 651 | O-linked_Glycosylation | TLFLRKSSPPALSAA HHHHHHCCCCHHHHH | 55412011 | ||
| 651 | Phosphorylation | TLFLRKSSPPALSAA HHHHHHCCCCHHHHH | - | ||
| 656 | O-linked_Glycosylation | KSSPPALSAALVAKG HCCCCHHHHHHHCCC | 55831309 | ||
| 666 | Phosphorylation | LVAKGTSSSPLAVAS HHCCCCCCCCCEECC | - | ||
| 673 | Phosphorylation | SSPLAVASGPAKSSS CCCCEECCCCCCCCH | - | ||
| 678 | Phosphorylation | VASGPAKSSSMTTLA ECCCCCCCCHHHHHH | 22210691 | ||
| 679 | Phosphorylation | ASGPAKSSSMTTLAK CCCCCCCCHHHHHHH | 29978859 | ||
| 680 | Phosphorylation | SGPAKSSSMTTLAKN CCCCCCCHHHHHHHH | 29978859 | ||
| 682 | Phosphorylation | PAKSSSMTTLAKNVT CCCCCHHHHHHHHCC | 29978859 | ||
| 683 | Phosphorylation | AKSSSMTTLAKNVTN CCCCHHHHHHHHCCC | 29978859 | ||
| 699 | Phosphorylation | AASGPKRTPGAVHTA HHCCCCCCCCCCCCC | 23607784 | ||
| 705 | Phosphorylation | RTPGAVHTAFPFTPT CCCCCCCCCCCCCCC | 23607784 | ||
| 710 | Phosphorylation | VHTAFPFTPTYMYAR CCCCCCCCCCEEEEE | 23607784 | ||
| 712 | Phosphorylation | TAFPFTPTYMYARTG CCCCCCCCEEEEECC | 23607784 | ||
| 713 | Phosphorylation | AFPFTPTYMYARTGH CCCCCCCEEEEECCC | 23607784 | ||
| 715 | Phosphorylation | PFTPTYMYARTGHTT CCCCCEEEEECCCCC | 23607784 | ||
| 718 | Phosphorylation | PTYMYARTGHTTSTH CCEEEEECCCCCCCC | - | ||
| 740 | Phosphorylation | DTASGLLSTTYLPRK CCCCCCCCCCCCCCC | - | ||
| 753 | O-linked_Glycosylation | RKPQAMHTGLPNPTN CCCCCCCCCCCCCCC | 55835471 | ||
| 759 | O-linked_Glycosylation | HTGLPNPTNLEMPRA CCCCCCCCCCCCCCC | 55411987 | ||
| 759 | Phosphorylation | HTGLPNPTNLEMPRA CCCCCCCCCCCCCCC | 28634120 | ||
| 775 | Phosphorylation | TPRPLTVTAALTSIT CCCCCCHHHHHHHHH | 22817900 | ||
| 779 | Phosphorylation | LTVTAALTSITASVK CCHHHHHHHHHEECC | 22817900 | ||
| 780 | Phosphorylation | TVTAALTSITASVKA CHHHHHHHHHEECCC | 22817900 | ||
| 782 | Phosphorylation | TAALTSITASVKATR HHHHHHHHEECCCCC | 22817900 | ||
| 784 | Phosphorylation | ALTSITASVKATRLP HHHHHHEECCCCCCC | 22817900 | ||
| 798 | Phosphorylation | PPLRAENTDAVLPAA CCCCCCCCCCCCCCC | 25137130 | ||
| 811 | Phosphorylation | AASAAVVTTGKMASN CCCEEEEECCCHHHC | 25137130 | ||
| 812 | Phosphorylation | ASAAVVTTGKMASNL CCEEEEECCCHHHCC | 25137130 | ||
| 843 | Phosphorylation | TQRRVQISESLKFSI HHCCCHHCHHHHHHH | 23898821 | ||
| 1105 | Phosphorylation | GRRFKRATTLGSYTV CCCCHHCCCCCCEEE | - | ||
| 1106 | Phosphorylation | RRFKRATTLGSYTVQ CCCHHCCCCCCEEEE | - | ||
| 1232 | Phosphorylation | KPVQGFDYAKQHLGQ CCCCCHHHHHHHHHC | 25884760 | ||
| 1274 | Phosphorylation | RDVAQDGSTIKTAKS CCCCCCCCCEECCCC | 29255136 | ||
| 1275 | Phosphorylation | DVAQDGSTIKTAKST CCCCCCCCEECCCCC | 29255136 | ||
| 1278 | Phosphorylation | QDGSTIKTAKSTETR CCCCCEECCCCCCCC | 29255136 | ||
| 1289 | Phosphorylation | TETRKSRSPSENGSV CCCCCCCCCCCCCCC | 25307156 | ||
| 1295 | Phosphorylation | RSPSENGSVISNESG CCCCCCCCCCCCCCC | 23911959 | ||
| 1298 | Phosphorylation | SENGSVISNESGKPS CCCCCCCCCCCCCCC | 23911959 | ||
| 1306 | Phosphorylation | NESGKPSSGRRSPQN CCCCCCCCCCCCHHH | 23911959 | ||
| 1310 | Phosphorylation | KPSSGRRSPQNVMAQ CCCCCCCCHHHHHHH | 30266825 | ||
| 1333 | Phosphorylation | RKRNVPASDEEEGAV HHCCCCCCCCCCCCE | 30266825 | ||
| 1355 | Phosphorylation | VAAEPFDTSSGSVQL EECCCCCCCCCEEEE | 25850435 | ||
| 1356 | Phosphorylation | AAEPFDTSSGSVQLI ECCCCCCCCCEEEEE | 25850435 | ||
| 1357 | Phosphorylation | AEPFDTSSGSVQLIA CCCCCCCCCEEEEEE | 25850435 | ||
| 1359 | Phosphorylation | PFDTSSGSVQLIAIK CCCCCCCEEEEEEEC | 25850435 | ||
| 1404 | Phosphorylation | QKSDIEHYRNKLRLK HHHHHHHHHHHHHHH | 29978859 | ||
| 1417 | Phosphorylation | LKAKRKGYYDFPAVE HHHHHCCCCCCCHHC | 25884760 | ||
| 1418 | Phosphorylation | KAKRKGYYDFPAVET HHHHCCCCCCCHHCC | 27174698 | ||
| 1425 | Phosphorylation | YDFPAVETSKGLTER CCCCHHCCCCCHHHH | 27174698 | ||
| 1426 | Phosphorylation | DFPAVETSKGLTERK CCCHHCCCCCHHHHH | 27174698 | ||
| 1427 | Ubiquitination | FPAVETSKGLTERKK CCHHCCCCCHHHHHH | - | ||
| 1430 | Phosphorylation | VETSKGLTERKKMYE HCCCCCHHHHHHHHH | 27174698 | ||
| 1473 | Phosphorylation | MKNSVYRSRQSLNSP HHHHHHHCHHHCCCC | 27732954 | ||
| 1476 | Phosphorylation | SVYRSRQSLNSPSPG HHHHCHHHCCCCCCC | 29255136 | ||
| 1479 | Phosphorylation | RSRQSLNSPSPGETE HCHHHCCCCCCCCCC | 27732954 | ||
| 1481 | Phosphorylation | RQSLNSPSPGETEMD HHHCCCCCCCCCCCE | 29255136 | ||
| 1485 | Phosphorylation | NSPSPGETEMDLLVT CCCCCCCCCCEEEEE | 24719451 | ||
| 1492 | Phosphorylation | TEMDLLVTRERPRRG CCCEEEEECCCCCCC | 24719451 | ||
| 1503 | Phosphorylation | PRRGIRNSGYDTEPE CCCCCCCCCCCCCHH | 29255136 | ||
| 1505 | Phosphorylation | RGIRNSGYDTEPEII CCCCCCCCCCCHHHH | 29255136 | ||
| 1507 | Phosphorylation | IRNSGYDTEPEIIEE CCCCCCCCCHHHHHH | 29255136 | ||
| 1515 | Phosphorylation | EPEIIEETNIDRVPE CHHHHHHCCCCCCCC | 25002506 | ||
| 1536 | Phosphorylation | SRQVKGHSETSTLSS CCCCCCCCCCCCCCC | 29507054 | ||
| 1538 | Phosphorylation | QVKGHSETSTLSSQP CCCCCCCCCCCCCCC | 25850435 | ||
| 1539 | Phosphorylation | VKGHSETSTLSSQPS CCCCCCCCCCCCCCC | 29255136 | ||
| 1540 | Phosphorylation | KGHSETSTLSSQPSI CCCCCCCCCCCCCCH | 29255136 | ||
| 1542 | Phosphorylation | HSETSTLSSQPSIDE CCCCCCCCCCCCHHH | 29255136 | ||
| 1543 | Phosphorylation | SETSTLSSQPSIDEV CCCCCCCCCCCHHHH | 29255136 | ||
| 1546 | Phosphorylation | STLSSQPSIDEVRQQ CCCCCCCCHHHHHHH | 29255136 | ||
| 1579 | Phosphorylation | QSRHQEAYGSAQHLP HHHHHHHHCCCCCCC | 25002506 | ||
| 1581 | Phosphorylation | RHQEAYGSAQHLPYS HHHHHHCCCCCCCHH | 25002506 | ||
| 1587 | Phosphorylation | GSAQHLPYSEVVTSA CCCCCCCHHHEEECC | 25002506 | ||
| 1588 | Phosphorylation | SAQHLPYSEVVTSAP CCCCCCHHHEEECCC | 25002506 | ||
| 1592 | Phosphorylation | LPYSEVVTSAPGTMT CCHHHEEECCCCCCC | 25002506 | ||
| 1593 | Phosphorylation | PYSEVVTSAPGTMTR CHHHEEECCCCCCCC | 25002506 | ||
| 1597 | Phosphorylation | VVTSAPGTMTRPRAG EEECCCCCCCCCCCC | 25002506 | ||
| 1599 | Phosphorylation | TSAPGTMTRPRAGVQ ECCCCCCCCCCCCCC | 25002506 | ||
| 1628 | Phosphorylation | PRPAYRFSQLPEMVM CCCCCCHHHCCHHHC | 25850435 | ||
| 1637 | Phosphorylation | LPEMVMGSPPPPVPP CCHHHCCCCCCCCCC | 25850435 | ||
| 1646 | O-linked_Glycosylation | PPPVPPRTGPVAVAS CCCCCCCCCCEEEEE | 28657654 | ||
| 1646 | Phosphorylation | PPPVPPRTGPVAVAS CCCCCCCCCCEEEEE | 22199227 | ||
| 1653 | Phosphorylation | TGPVAVASLRRSTSD CCCEEEEECCCCCCC | 22199227 | ||
| 1657 | Phosphorylation | AVASLRRSTSDIGSK EEEECCCCCCCCCCC | 22199227 | ||
| 1658 | Phosphorylation | VASLRRSTSDIGSKT EEECCCCCCCCCCCC | 24719451 | ||
| 1659 | Phosphorylation | ASLRRSTSDIGSKTR EECCCCCCCCCCCCC | 22199227 | ||
| 1663 | Phosphorylation | RSTSDIGSKTRMAES CCCCCCCCCCCCCCC | 22199227 | ||
| 1681 | Phosphorylation | EPAQLHDSASFTQMS CCCCCCCCCCCEECC | 26852163 | ||
| 1683 | Phosphorylation | AQLHDSASFTQMSRG CCCCCCCCCEECCCC | 26852163 | ||
| 1685 | Phosphorylation | LHDSASFTQMSRGPV CCCCCCCEECCCCCC | 26852163 | ||
| 1688 | Phosphorylation | SASFTQMSRGPVSVT CCCCEECCCCCCCEE | 26852163 | ||
| 1769 | Phosphorylation | YIEAYPRSRYPQSSP HHHCCCCCCCCCCCC | 23403867 | ||
| 1771 | Phosphorylation | EAYPRSRYPQSSPSR HCCCCCCCCCCCCCC | 23403867 | ||
| 1774 | Phosphorylation | PRSRYPQSSPSRLPR CCCCCCCCCCCCCCC | 23403867 | ||
| 1775 | Phosphorylation | RSRYPQSSPSRLPRQ CCCCCCCCCCCCCCC | 23403867 | ||
| 1777 | Phosphorylation | RYPQSSPSRLPRQYS CCCCCCCCCCCCCCC | 23403867 | ||
| 1784 | Phosphorylation | SRLPRQYSQPANLHP CCCCCCCCCCCCCCC | - | ||
| 1839 | Acetylation | EEVAKLAKKQTDMFE HHHHHHHHHCCCCCC | 130757 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of K154L_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of K154L_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of K154L_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of K154L_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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