JMJD8_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: JMJD8_HUMAN
• UniProt AC: Q96S16
• Protein Name: JmjC domain-containing protein 8
• Gene Name: JMJD8
• Organism: Homo sapiens (Human).
• Sequence Length: 334
• Protein Sequence: MVTGGAHSRSRGGLPSASRRGLFRGGPKEVTSGVRPGSRPLPRRRSCRPMAGGWAQGSRRAARLPEGGRLMAPASRLLALWALAAVALPGSGAEGDGGWRPGGPGAVAEEERCTVERRADLTYAEFVQQYAFVRPVILQGLTDNSRFRALCSRDRLLASFGDRVVRLSTANTYSYHKVDLPFQEYVEQLLHPQDPTSLGNDTLYFFGDNNFTEWASLFRHYSPPPFGLLGTAPAYSFGIAGAGSGVPFHWHGPGYSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLRDTYPALPPSARPLECTIRAGEVLYFPDRWWHATLNLDTSVFISTFLG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	Phosphorylation	AGGWAQGSRRAARLP CCCCHHCCHHHCCCC	13.40	-
103	Phosphorylation	DGGWRPGGPGAVAEE CCCCCCCCCCCCCCH	21.83	-
130	Phosphorylation	YAEFVQQYAFVRPVI HHHHHHHHHCHHHHH	5.73	22817900
130	N-linked_Glycosylation	YAEFVQQYAFVRPVI HHHHHHHHHCHHHHH	5.73	-
140	N-linked_Glycosylation	VRPVILQGLTDNSRF HHHHHHHCCCCCHHH	27.40	-
152	Phosphorylation	SRFRALCSRDRLLAS HHHHHHHCHHHHHHH	37.76	25278378
159	Phosphorylation	SRDRLLASFGDRVVR CHHHHHHHHCCEEEE	29.72	24719451
174	O-linked_Glycosylation	LSTANTYSYHKVDLP ECCCCCCCEEECCCC	20.79	30620550
209	N-linked_Glycosylation	TLYFFGDNNFTEWAS CEEEECCCCHHHHHH	45.99	-
281	Phosphorylation	PEFHPNKTTLAWLRD CCCCCCCCCHHHHHH	33.41	26552605
282	Phosphorylation	EFHPNKTTLAWLRDT CCCCCCCCHHHHHHH	18.98	26552605
289	Phosphorylation	TLAWLRDTYPALPPS CHHHHHHHCCCCCCC	25.60	26552605
290	Phosphorylation	LAWLRDTYPALPPSA HHHHHHHCCCCCCCC	7.27	26552605
296	Phosphorylation	TYPALPPSARPLECT HCCCCCCCCCCCEEE	34.66	26552605

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of JMJD8_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of JMJD8_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of JMJD8_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of JMJD8_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.