JKIP3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: JKIP3_MOUSE
• UniProt AC: Q5DTN8
• Protein Name: Janus kinase and microtubule-interacting protein 3
• Gene Name: Jakmip3
• Organism: Mus musculus (Mouse).
• Sequence Length: 844
• Subcellular Localization: Golgi apparatus .
• Protein Sequence: MSKKGAGSRAKGDKAETLAALQAANEELRAKLTDIQIELQQEKSKVSKVEREKSQELKQVREHEQRKHAVLVTELKTKLHEEKMKELQAVREALLRQHEAELLRVIKIKDNENQRLQALLNTLRDGAPDKVKTVLLCEAKEEAKKGFEVEKVKMQQEISELKGAKKQVEEALTMVIQADKIKAAEIRSVYHLHQEEITRIKKECEREIRRLMEEIRFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQAKEAERHPGSPRRELPYASGAGDASDHSGSPEQQLDEKDARRFQLKIAELSAIIRKLEDRNALLSEERNELLKRLREAESQYKPLLDKNKRLTRKNEDLSHTLRRIESKLKFVTQENIEMRQRAGIIRRPSSLNDLDQSQDEREIDFLKLQIVEQQNLIDELSKTLETAGYVKSVLERDKLLRYRKQRKKMAKLPKPVVVETFFGYDEEASLESDGSSISYQTDRTDQTPCTPEDDLEEGMAKEETELRFRQLTMEYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEIQRAQTRVEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQMETEEARLKHEVQDAKDQNELLEFRILELEERERKSPAINFHHTPFVDGKSPLQVYCEAEGVTDILVTELMKKLDILGDNANLTNEEQVVVIQARTVLTLAEKWLQRIEETESALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQAHKHILELEAMLYDALQQEAGAKVAELLSEEEREKLKVAVEQWKRQVMSELRERDAQILRERMELLQIAQQRIKELEERIETQKRQIKELEEKFLFLFLFFSLAFILWS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MSKKGAGSRAKGDKA CCCCCCCCCCCCCHH	28.65	-
262	Phosphorylation	EAERHPGSPRRELPY HHHHCCCCCCCCCCC	21.49	25521595
269	Phosphorylation	SPRRELPYASGAGDA CCCCCCCCCCCCCCC	26.48	29899451
271	Phosphorylation	RRELPYASGAGDASD CCCCCCCCCCCCCCC	24.27	29899451
277	Phosphorylation	ASGAGDASDHSGSPE CCCCCCCCCCCCCHH	40.36	29899451
280	Phosphorylation	AGDASDHSGSPEQQL CCCCCCCCCCHHHHC	46.05	29899451
282	Phosphorylation	DASDHSGSPEQQLDE CCCCCCCCHHHHCCH	28.42	29899451
325	Ubiquitination	EERNELLKRLREAES HHHHHHHHHHHHHHH	63.11	27667366
383	Phosphorylation	AGIIRRPSSLNDLDQ CCCCCCCCCCCCCCC	45.72	25521595
384	Phosphorylation	GIIRRPSSLNDLDQS CCCCCCCCCCCCCCC	33.60	25521595
391	Phosphorylation	SLNDLDQSQDEREID CCCCCCCCCCHHHHH	38.99	29899451
425	Ubiquitination	LETAGYVKSVLERDK HHHHHHHHHHHHHHH	26.77	-
484	Phosphorylation	RTDQTPCTPEDDLEE CCCCCCCCCHHHHHC	30.80	25521595
622	Phosphorylation	LEERERKSPAINFHH HHHHHCCCCCCCCCC	26.28	22324799
670	Phosphorylation	LGDNANLTNEEQVVV CCCCCCCCCHHHEEE	40.15	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of JKIP3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of JKIP3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of JKIP3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of JKIP3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.