dbPTM

JAM3_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	JAM3_RAT
UniProt AC	Q68FQ2
Protein Name	Junctional adhesion molecule C
Gene Name	Jam3
Organism	Rattus norvegicus (Rat).
Sequence Length	310
Subcellular Localization	Cell membrane Single-pass type I membrane protein . Cell junction, desmosome . Secreted, extracellular space .
Protein Description	May participate in cell-cell adhesion distinct from tight junctions..
Protein Sequence	MALSRRLRLRLCARLPDFFLLLLFRGCVIEAVNLKSSNRNPVVHEFESVELSCIITDSQTNDPRIEWKKIQDGQTTYVYFDNKIQGDLAGRTDVFGKTSLRIWNVTRSDSAIYRCEVVALNDRKEVDELTIELIVQVKPVAPVCRVPKAVPVGKAATLQCQESEGYPRPYYSWYRNDVPLPTDSRANPRFQNSSFHVNSETGTLVFSAVHKEDSGQYYCIASNDAGAARCEGQDMEVYDLNIAGIIGGVLVVLIVLAVITMGICCAYRRGCFISSKQDGESYKSPGKHEGVNYIRTSEEGDFRHKSSFVI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	N-linked_Glycosylation	KTSLRIWNVTRSDSA CEEEEEEEECCCCCE	23.94	-
192	N-linked_Glycosylation	RANPRFQNSSFHVNS CCCCCCCCCCEEEEC	36.59	24090084
264	S-palmitoylation	AVITMGICCAYRRGC HHHHHHHHHHHHCCC	0.62	-
265	S-palmitoylation	VITMGICCAYRRGCF HHHHHHHHHHHCCCE	3.35	-
287	Ubiquitination	ESYKSPGKHEGVNYI CCCCCCCCCCCCCEE	41.70	-
293	Phosphorylation	GKHEGVNYIRTSEEG CCCCCCCEEECCCCC	6.86	25575281
296	Phosphorylation	EGVNYIRTSEEGDFR CCCCEEECCCCCCCC	30.82	25575281
297	Phosphorylation	GVNYIRTSEEGDFRH CCCEEECCCCCCCCC	24.65	25575281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of JAM3_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of JAM3_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of JAM3_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of JAM3_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of JAM3_RAT

Related Literatures of Post-Translational Modification