dbPTM

ITN1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ITN1_ARATH
UniProt AC	Q9C7A2
Protein Name	Ankyrin repeat-containing protein ITN1
Gene Name	ITN1 {ECO:0000303\|PubMed:18643991}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	590
Subcellular Localization	Cell membrane Multi-pass membrane protein .
Protein Description	Involved in salt stress tolerance. May act through abscisic acid (ABA) signaling pathways and promote reactive oxygen species (ROS) production..
Protein Sequence	MAASSYVDGERDMEKGGMILLQSSENQNPMIDPSPTPSPSATATAPALVLSNSGKRMDQAGKKKYVKQVTGRHNDTELHLAAQRGDLAAVQQILKDINSQMEGILSGEEFDAEVAEIRASIVNEVNELGETALFTAADKGHLDVVKELLKYSSRESIAKKNRSGYDPLHIAAIQGHHAIVEVLLDHDATLSQTFGPSNATPLVSAAMRGHTEVVNQLLSKAGNLLEISRSNNKNALHLAARQGHVEVIKALLSKDPQLARRIDKKGQTALHMAVKGQSSEVVKLLLDADPAIVMQPDKSCNTALHVATRKKRAEIVELLLSLPDTNANTLTRDHKTALDIAEGLPLSEESSYIKECLARSGALRANELNQPRDELRSTVTQIKNDVHIQLEQTKRTNKNVHNISKELRKLHREGINNATNSVTVVAVLFATVAFAAIFTVPGGDNNDGSAVVVGRASFKIFFIFNALALFTSLAVVVVQITLVRGETKAEKRVVEVINKLMWLASMCTSVAFLASSYIVVGRKNEWAAELVTVVGGVIMAGVLGTMTYYVVKSKRTRSMRKKVKSARRSGSNSWHHSDFSNSEVDPIFAI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
419	Phosphorylation	REGINNATNSVTVVA HHHCHHHCCHHHHHH	25368622
421	Phosphorylation	GINNATNSVTVVAVL HCHHHCCHHHHHHHH	25368622
423	Phosphorylation	NNATNSVTVVAVLFA HHHCCHHHHHHHHHH	25368622
431	Phosphorylation	VVAVLFATVAFAAIF HHHHHHHHHHHHHHE	25368622
439	Phosphorylation	VAFAAIFTVPGGDNN HHHHHHEECCCCCCC	25368622
449	Phosphorylation	GGDNNDGSAVVVGRA CCCCCCCCEEEEECH	25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ITN1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ITN1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ITN1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
REM19_ARATH	RTV1	physical	22664102

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ITN1_ARATH

Related Literatures of Post-Translational Modification