ITM2A_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ITM2A_MOUSE
• UniProt AC: Q61500
• Protein Name: Integral membrane protein 2A
• Gene Name: Itm2a
• Organism: Mus musculus (Mouse).
• Sequence Length: 263
• Subcellular Localization: Membrane ; Single-pass type II membrane protein .
• Protein Sequence: MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILTGKELRVVPQEKDGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSEDPVNSIPGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Ubiquitination	-----MVKIAFNTPT -----CCEEEECCCC	27.33	-
14	Ubiquitination	NTPTAVQKEEARQDV CCCCHHCHHHHHHHH	51.42	27667366
37	Ubiquitination	RAQILTGKELRVVPQ HHHHHCCCEEEEECC	48.63	-
46	Ubiquitination	LRVVPQEKDGSSGRC EEEECCCCCCCCHHH	63.24	27667366
166	N-linked_Glycosylation	NCYLMPLNTSIVMTP CCEEEECCCCEEECC	26.38	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ITM2A_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ITM2A_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ITM2A_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of ITM2A_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.