dbPTM

IQD14_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	IQD14_ARATH
UniProt AC	Q8LPG9
Protein Name	Protein IQ-DOMAIN 14
Gene Name	IQD14
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	668
Subcellular Localization
Protein Description	May be involved in cooperative interactions with calmodulins or calmodulin-like proteins. May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity)..
Protein Sequence	MVKKGSWFSAIKRVFTPHSKEKLANEPERKSGKEKKKKGFGKLRHGETNSFLPIFREPSSIEKILGEAERDHNLVFRPPTPDRPNPYSASPPPRPASPRVASPRPTSPRVASPRVPSPRAEVPRTLSPKPPSPRAEVPRSLSPKPPSPRADLPRSLSPKPFDRSKPSSASANAPPTLRPASTRVPSQRITPHSVPSPRPSSPRGASPQAISSKPPSPRAEPPTLDTPRPPSPRAASLRADPPRLDAARPTTPRPPSPLADAPRLDAPRPTTPKPPSPRSDPPRLDAPRPTTPKPPSPRSVSPRAVQRREIVYRPEPTLPVQHASATKIQGAFRGYMARKSFRALKGLVRLQGVVRGYSVKRQTINAMKYMQQVVRVQSQIQSRRIKMLENQAQVEKDEAKWAASEAGNDNWDDSVLTKEERDSRSQRKTDAIIKRERSMAYAYSRKLWKNSPKSTQDNRSFPQWWNWVDRQNPLASPAPSYSQPQRDFRLTPSRLCPSPLSQSSKQHHIRLDNHFDTSTPRSSRSTFHTPSRPIHTGTSRYSRGRLRGQDSPFKDDDSLTSCPPFPSYMAPTVSAKAKVRPNSNPKERVMGTPVSEKRRMSYPPTQDTFRWNKGSLVMSNSSSHRGPGSPGGVVLEKHKTLKSVGNLSIGSTASMATTVGRKEFNRFV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	GKLRHGETNSFLPIF CCCCCCCCCCCCHHC	40.53	17317660
50	Phosphorylation	LRHGETNSFLPIFRE CCCCCCCCCCHHCCC	35.26	17317660
59	Phosphorylation	LPIFREPSSIEKILG CHHCCCCHHHHHHHC	38.91	30589143
60	Phosphorylation	PIFREPSSIEKILGE HHCCCCHHHHHHHCH	45.54	30589143
80	Phosphorylation	NLVFRPPTPDRPNPY CCEECCCCCCCCCCC	40.27	29654922
87	Phosphorylation	TPDRPNPYSASPPPR CCCCCCCCCCCCCCC	24.41	23660473
88	Phosphorylation	PDRPNPYSASPPPRP CCCCCCCCCCCCCCC	24.43	19880383
90	Phosphorylation	RPNPYSASPPPRPAS CCCCCCCCCCCCCCC	31.81	23660473
97	Phosphorylation	SPPPRPASPRVASPR CCCCCCCCCCCCCCC	18.87	29654922
102	Phosphorylation	PASPRVASPRPTSPR CCCCCCCCCCCCCCC	20.70	23776212
106	Phosphorylation	RVASPRPTSPRVASP CCCCCCCCCCCCCCC	53.28	23776212
107	Phosphorylation	VASPRPTSPRVASPR CCCCCCCCCCCCCCC	17.25	23776212
112	Phosphorylation	PTSPRVASPRVPSPR CCCCCCCCCCCCCCC	15.47	19376835
117	Phosphorylation	VASPRVPSPRAEVPR CCCCCCCCCCCCCCC	24.94	29654922
125	Phosphorylation	PRAEVPRTLSPKPPS CCCCCCCCCCCCCCC	26.05	23776212
127	Phosphorylation	AEVPRTLSPKPPSPR CCCCCCCCCCCCCCC	30.20	19880383
132	Phosphorylation	TLSPKPPSPRAEVPR CCCCCCCCCCCCCCC	35.23	19880383
140	Phosphorylation	PRAEVPRSLSPKPPS CCCCCCCCCCCCCCC	27.42	23776212
142	Phosphorylation	AEVPRSLSPKPPSPR CCCCCCCCCCCCCCC	31.93	19880383
147	Phosphorylation	SLSPKPPSPRADLPR CCCCCCCCCCCCCCC	35.23	30291188
155	Phosphorylation	PRADLPRSLSPKPFD CCCCCCCCCCCCCCC	31.12	23776212
157	Phosphorylation	ADLPRSLSPKPFDRS CCCCCCCCCCCCCCC	31.93	30291188
193	Phosphorylation	SQRITPHSVPSPRPS CCCCCCCCCCCCCCC	36.61	19880383
196	Phosphorylation	ITPHSVPSPRPSSPR CCCCCCCCCCCCCCC	31.24	27532006
200	Phosphorylation	SVPSPRPSSPRGASP CCCCCCCCCCCCCCC	55.01	29654922
201	Phosphorylation	VPSPRPSSPRGASPQ CCCCCCCCCCCCCCC	22.69	19880383
206	Phosphorylation	PSSPRGASPQAISSK CCCCCCCCCCHHHCC	21.99	30291188
211	Phosphorylation	GASPQAISSKPPSPR CCCCCHHHCCCCCCC	35.01	23776212
212	Phosphorylation	ASPQAISSKPPSPRA CCCCHHHCCCCCCCC	42.97	23776212
216	Phosphorylation	AISSKPPSPRAEPPT HHHCCCCCCCCCCCC	35.23	30291188
223	Phosphorylation	SPRAEPPTLDTPRPP CCCCCCCCCCCCCCC	48.24	23776212
226	Phosphorylation	AEPPTLDTPRPPSPR CCCCCCCCCCCCCCC	25.06	30291188
231	Phosphorylation	LDTPRPPSPRAASLR CCCCCCCCCCHHHHC	29.69	30291188
236	Phosphorylation	PPSPRAASLRADPPR CCCCCHHHHCCCCCC	19.87	30407730
250	Phosphorylation	RLDAARPTTPRPPSP CCCCCCCCCCCCCCC	43.83	17317660
251	Phosphorylation	LDAARPTTPRPPSPL CCCCCCCCCCCCCCC	21.71	23776212
256	Phosphorylation	PTTPRPPSPLADAPR CCCCCCCCCCCCCCC	34.92	17317660
270	Phosphorylation	RLDAPRPTTPKPPSP CCCCCCCCCCCCCCC	57.94	17317660
271	Phosphorylation	LDAPRPTTPKPPSPR CCCCCCCCCCCCCCC	31.81	23776212
276	Phosphorylation	PTTPKPPSPRSDPPR CCCCCCCCCCCCCCC	41.28	30291188
279	Phosphorylation	PKPPSPRSDPPRLDA CCCCCCCCCCCCCCC	58.83	23776212
290	Phosphorylation	RLDAPRPTTPKPPSP CCCCCCCCCCCCCCC	57.94	17317660
291	Phosphorylation	LDAPRPTTPKPPSPR CCCCCCCCCCCCCCC	31.81	23776212
296	Phosphorylation	PTTPKPPSPRSVSPR CCCCCCCCCCCCCHH	41.28	30291188
378	Phosphorylation	QQVVRVQSQIQSRRI HHHHHHHHHHHHHHH	26.79	25561503
404	Phosphorylation	DEAKWAASEAGNDNW HHHHHHHHHHCCCCC	21.89	30291188
438	Phosphorylation	AIIKRERSMAYAYSR HHHHHHHHHHHHHHH	11.74	30407730
443	Phosphorylation	ERSMAYAYSRKLWKN HHHHHHHHHHHHHHC	9.06	30407730
444	Phosphorylation	RSMAYAYSRKLWKNS HHHHHHHHHHHHHCC	18.11	30407730
476	Phosphorylation	DRQNPLASPAPSYSQ HHCCCCCCCCCCCCC	29.31	30291188
480	Phosphorylation	PLASPAPSYSQPQRD CCCCCCCCCCCCCCC	39.25	30291188
481	Phosphorylation	LASPAPSYSQPQRDF CCCCCCCCCCCCCCC	15.40	19880383
482	Phosphorylation	ASPAPSYSQPQRDFR CCCCCCCCCCCCCCC	39.46	25561503
491	Phosphorylation	PQRDFRLTPSRLCPS CCCCCCCCHHHCCCC	18.24	30291188
498	Phosphorylation	TPSRLCPSPLSQSSK CHHHCCCCCCCCCCC	37.16	30291188
501	Phosphorylation	RLCPSPLSQSSKQHH HCCCCCCCCCCCCCC	31.25	23111157
503	Phosphorylation	CPSPLSQSSKQHHIR CCCCCCCCCCCCCEE	35.81	30407730
504	Phosphorylation	PSPLSQSSKQHHIRL CCCCCCCCCCCCEEE	28.79	25561503
517	Phosphorylation	RLDNHFDTSTPRSSR EECCCCCCCCCCCCC	33.29	30407730
518	Phosphorylation	LDNHFDTSTPRSSRS ECCCCCCCCCCCCCC	37.95	23111157
519	Phosphorylation	DNHFDTSTPRSSRST CCCCCCCCCCCCCCC	25.47	23111157
522	Phosphorylation	FDTSTPRSSRSTFHT CCCCCCCCCCCCCCC	31.16	25561503
523	Phosphorylation	DTSTPRSSRSTFHTP CCCCCCCCCCCCCCC	31.37	25561503
526	Phosphorylation	TPRSSRSTFHTPSRP CCCCCCCCCCCCCCC	20.51	29654922
529	Phosphorylation	SSRSTFHTPSRPIHT CCCCCCCCCCCCCCC	20.83	25561503
551	Phosphorylation	GRLRGQDSPFKDDDS CCCCCCCCCCCCCCC	25.09	23111157
558	Phosphorylation	SPFKDDDSLTSCPPF CCCCCCCCCCCCCCC	40.31	23111157
583	Phosphorylation	KAKVRPNSNPKERVM CCCCCCCCCHHHCCC	58.13	25561503
592	Phosphorylation	PKERVMGTPVSEKRR HHHCCCCCCCCCCCC	11.47	23111157
595	Phosphorylation	RVMGTPVSEKRRMSY CCCCCCCCCCCCCCC	38.31	30407730
601	Phosphorylation	VSEKRRMSYPPTQDT CCCCCCCCCCCCCCC	32.45	25561503
615	Phosphorylation	TFRWNKGSLVMSNSS CCCCCCCCEEECCCC	21.28	23776212
619	Phosphorylation	NKGSLVMSNSSSHRG CCCCEEECCCCCCCC	26.53	23776212
621	Phosphorylation	GSLVMSNSSSHRGPG CCEEECCCCCCCCCC	26.38	23776212
622	Phosphorylation	SLVMSNSSSHRGPGS CEEECCCCCCCCCCC	34.12	23776212
623	Phosphorylation	LVMSNSSSHRGPGSP EEECCCCCCCCCCCC	19.61	23776212
629	Phosphorylation	SSHRGPGSPGGVVLE CCCCCCCCCCCEEEE	24.41	30291188
640	Phosphorylation	VVLEKHKTLKSVGNL EEEEECCCCCEECCC	38.85	28295753
643	Phosphorylation	EKHKTLKSVGNLSIG EECCCCCEECCCCCC	38.07	30291188
648	Phosphorylation	LKSVGNLSIGSTASM CCEECCCCCCCCCCC	28.98	17317660
651	Phosphorylation	VGNLSIGSTASMATT ECCCCCCCCCCCCHH	21.09	28295753
652	Phosphorylation	GNLSIGSTASMATTV CCCCCCCCCCCCHHC	19.96	28295753
654	Phosphorylation	LSIGSTASMATTVGR CCCCCCCCCCHHCCH	14.72	28295753
657	Phosphorylation	GSTASMATTVGRKEF CCCCCCCHHCCHHHH	17.24	28295753
658	Phosphorylation	STASMATTVGRKEFN CCCCCCHHCCHHHHH	16.07	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of IQD14_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of IQD14_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of IQD14_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of IQD14_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of IQD14_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102; THR-106; SER-107;SER-112; SER-127; SER-132; SER-157; SER-231 AND SER-629, AND MASSSPECTROMETRY.	19376835 [Abstract]
"Quantitative phosphoproteomics of early elicitor signaling inArabidopsis."; Benschop J.J., Mohammed S., O'Flaherty M., Heck A.J.R., Slijper M.,Menke F.L.H.; Mol. Cell. Proteomics 6:1198-1214(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132; SER-142; SER-147;SER-212; SER-216; THR-290 AND SER-296, AND MASS SPECTROMETRY.	17317660 [Abstract]