IQCK_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IQCK_HUMAN
• UniProt AC: Q8N0W5
• Protein Name: IQ domain-containing protein K
• Gene Name: IQCK
• Organism: Homo sapiens (Human).
• Sequence Length: 287
• Protein Sequence: MAAPRQIPSHIVRLKPSCSTDSSFTRTPVPTVSLASRELPVSSWQVTEPSSKNLWEQICKEYEAEQPPFPEGYKVKQEPVITVAPVEEMLFHGFSAEHYFPVSHFTMISRTPCPQDKSETINPKTCSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSIPFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQWQKKLREAKHIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKIPSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	AAPRQIPSHIVRLKP CCCCCCCCCEEEECC	27.72	-
17	Phosphorylation	HIVRLKPSCSTDSSF CEEEECCCCCCCCCC	21.07	30576142
22	Phosphorylation	KPSCSTDSSFTRTPV CCCCCCCCCCCCCCC	27.69	-
23	Phosphorylation	PSCSTDSSFTRTPVP CCCCCCCCCCCCCCC	33.19	30576142
27	Phosphorylation	TDSSFTRTPVPTVSL CCCCCCCCCCCEEEE	26.11	22817900
36	Phosphorylation	VPTVSLASRELPVSS CCEEEEECCCCCCCE	31.42	30576142
42	Phosphorylation	ASRELPVSSWQVTEP ECCCCCCCEEECCCC	24.74	25693802
43	Phosphorylation	SRELPVSSWQVTEPS CCCCCCCEEECCCCC	23.05	25693802
47	Phosphorylation	PVSSWQVTEPSSKNL CCCEEECCCCCCCCH	27.38	25693802
74	Ubiquitination	PPFPEGYKVKQEPVI CCCCCCCCCCCCCCE	54.54	-
117	Ubiquitination	RTPCPQDKSETINPK CCCCCCCCCCCCCCC	44.97	-
286	Phosphorylation	AAKMKIPSS------ HHHCCCCCC------	52.75	23186163
287	Phosphorylation	AKMKIPSS------- HHCCCCCC-------	38.60	23186163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IQCK_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IQCK_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IQCK_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of IQCK_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.