IP5P2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IP5P2_ARATH
• UniProt AC: Q9FUR2
• Protein Name: Type I inositol polyphosphate 5-phosphatase 2 {ECO:0000303|PubMed:11402208}
• Gene Name: IP5P2 {ECO:0000303|PubMed:11340187}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 646
• Protein Description: Has phosphatase activity toward Ins(1,4,5)P3 and Ins(1,3,4,5)P4. Seems to be involved in the abscisic acid (ABA) signaling pathway. [PubMed: 11340187 Could also be able to hydrolyze PtdIns(4,5)P2 and PtdIns(3,4,5)P3]
• Protein Sequence: MKTRRGKRPERFWPSIVMNKWLNRKPKVYDFSEDEIDTEPESEDDVCSVKDVPNVHCVTDEDSHNGRRGSEADHGNNISDGGVSVRGGYQRKHRRGKSETLRAQYINTKDIKVTVATWNVAGKRPSDDLEIEDWLSTDNPSDIYIIGFQEVVPLNAGNVFGAEDRGPIPKWESIIRRTLNKSNKESVYDQSPSCNNNALHRSHSAPSSPILAQEANSIISHVMVENLVADHSLDLATNEFIDAATALPSLEPQRNPNMDWPELALDSNPQIVGSEGKLRRVFSSNATLGFKLPENPSGASRFASEARQLKRSRSFETLNLSWNDIKEEIDNRSSSSSEAEEAAKIMHDDSSDGDSSSQDEEDGDKIRNSYGLPEDLVEECRKVKDSQKYVRIVSKQMVGIYVSVWIRRRLRRHVNNLKVSPVGVGLMGYMGNKGSVSISMTLYQSRMCFVCSHLTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQPRTIPCHDQVFWFGDLNYRLNMSDGEVRKLVSQKRWDELKNSDQLIRELRRGHVFDGWREGPIKFPPTYKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIRQECYKRSEIRMSDHRPVTSIFNVGVEVFDHRKLQRALHVNNAAASAVHPEPSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
283	Phosphorylation	GKLRRVFSSNATLGF CCEEEEECCCCEEEE	21.59	19376835
284	Phosphorylation	KLRRVFSSNATLGFK CEEEEECCCCEEEEE	21.01	19376835
287	Phosphorylation	RVFSSNATLGFKLPE EEECCCCEEEEECCC	31.50	19376835
297	Phosphorylation	FKLPENPSGASRFAS EECCCCCCHHHHHHH	59.58	19376835
300	Phosphorylation	PENPSGASRFASEAR CCCCCHHHHHHHHHH	31.30	19376835
314	Phosphorylation	RQLKRSRSFETLNLS HHHHHCCCCCCCCCC	28.78	26091701

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IP5P2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IP5P2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IP5P2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of IP5P2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.