IMPG1_HUMAN - dbPTM
IMPG1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IMPG1_HUMAN
UniProt AC Q17R60
Protein Name Interphotoreceptor matrix proteoglycan 1
Gene Name IMPG1 {ECO:0000312|EMBL:AAI17453.1}
Organism Homo sapiens (Human).
Sequence Length 797
Subcellular Localization Secreted .
Protein Description May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix..
Protein Sequence MYLETRRAIFVFWIFLQVQGTKDISINIYHSETKDIDNPPRNETTESTEKMYKMSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDWVSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFPDRKDEISAEKTLGEPGETIVISTDVANVSLGPFPLTPDDTLLNEILDNTLNDTKMPTTERETEFAVLEEQRVELSVSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSSTEMQLTAIFKRHSAEAKSPASDLLSFDSNKIESEEVYHGTMEEDKQPEIYLTATDLKRLISKALEEEQSLDVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPELPPVEPQLETVDGAEHGLPDTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATDQTMLVPGLTIPTSDYSAISQLALGISHPPASSDDSRSSAGGEDMVRHLDEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTSSMTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQLEILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPADQADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQGSLDGLEPGLCGPGTKECEVLQGKGAPCRLPDHSENQAYKTSVKKFQNQQNNKVISKRNSELLTVEYEEFNHQDWEGN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
21PhosphorylationIFLQVQGTKDISINI
HHHHCCCCCCEEEEE		14.4124719451
42N-linked_GlycosylationDIDNPPRNETTESTE
CCCCCCCCCCCHHHH		57.66UniProtKB CARBOHYD
44PhosphorylationDNPPRNETTESTEKM
CCCCCCCCCHHHHHH		39.14-
92PhosphorylationSMKQILDSLQAYYRL
HHHHHHHHHHHHHHH		20.9518510355
96PhosphorylationILDSLQAYYRLRVCQ
HHHHHHHHHHHHHHH		3.9924043423
97PhosphorylationLDSLQAYYRLRVCQE
HHHHHHHHHHHHHHH		13.2424043423
143N-linked_GlycosylationCLFDIGKNFSNSQEH
EEEEECCCCCCCHHH		40.12UniProtKB CARBOHYD
191N-linked_GlycosylationVISTDVANVSLGPFP
EEEECCCCCCCCCCC		24.61UniProtKB CARBOHYD
213PhosphorylationLNEILDNTLNDTKMP
HHHHHHHCCCCCCCC		26.9724275569
215N-linked_GlycosylationEILDNTLNDTKMPTT
HHHHHCCCCCCCCCC		53.52UniProtKB CARBOHYD
217PhosphorylationLDNTLNDTKMPTTER
HHHCCCCCCCCCCHH		28.3324275569
221PhosphorylationLNDTKMPTTERETEF
CCCCCCCCCHHHCCC		37.4823403867
222PhosphorylationNDTKMPTTERETEFA
CCCCCCCCHHHCCCH		27.4623403867
241PhosphorylationQRVELSVSLVNQKFK
HEEEEEHHHHHHHHH		24.1926546556
312PhosphorylationTAIFKRHSAEAKSPA
HHHHHHCCCCCCCCH		31.6621712546
317PhosphorylationRHSAEAKSPASDLLS
HCCCCCCCCHHHHHC		32.5221712546
320PhosphorylationAEAKSPASDLLSFDS
CCCCCCHHHHHCCCC		31.9821712546
403O-linked_GlycosylationPTSFAVITEDATLSP
CCEEEEEECCCCCCC		22.63UniProtKB CARBOHYD
421O-linked_GlycosylationPVEPQLETVDGAEHG
CCCCCEEECCCCCCC		32.27UniProtKB CARBOHYD
432O-linked_GlycosylationAEHGLPDTSWSPPAM
CCCCCCCCCCCCCCC		30.10UniProtKB CARBOHYD
442O-linked_GlycosylationSPPAMASTSLSEAPP
CCCCCCCCCHHHCCC		24.93UniProtKB CARBOHYD
592N-linked_GlycosylationAFSNDLFNKSSLEYR
HCCCCCCCCHHHHHH		51.07UniProtKB CARBOHYD
616N-linked_GlycosylationLVPYLRSNLTGFKQL
HHHHHHCCCCCCEEE		34.88UniProtKB CARBOHYD
630N-linked_GlycosylationLEILNFRNGSVIVNS
EEEEECCCCCEEECC		42.84UniProtKB CARBOHYD
632PhosphorylationILNFRNGSVIVNSKM
EEECCCCCEEECCCC		16.54-
637PhosphorylationNGSVIVNSKMKFAKS
CCCEEECCCCCCCCC		24.1930206219
648N-linked_GlycosylationFAKSVPYNLTKAVHG
CCCCCCCCHHHHHHH		34.85UniProtKB CARBOHYD
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IMPG1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IMPG1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IMPG1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of IMPG1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
616151Macular dystrophy, vitelliform, 4 (VMD4)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IMPG1_HUMAN

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Related Literatures of Post-Translational Modification

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