IL17B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IL17B_HUMAN
• UniProt AC: Q9UHF5
• Protein Name: Interleukin-17B
• Gene Name: IL17B
• Organism: Homo sapiens (Human).
• Sequence Length: 180
• Subcellular Localization: Secreted.
• Protein Description: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1..
• Protein Sequence: MDWPHNLLFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
75	N-linked_Glycosylation	EMVAQLRNSSELAQR HHHHHHHCCHHHHHH	59.48	UniProtKB CARBOHYD
137	Phosphorylation	FTMQEDRSMVSVPVF CCCCCCHHCCCCCCC	35.54	29083192
140	Phosphorylation	QEDRSMVSVPVFSQV CCCHHCCCCCCCCCC	16.44	29083192
145	Phosphorylation	MVSVPVFSQVPVRRR CCCCCCCCCCCCCCC	30.42	29083192

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IL17B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IL17B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IL17B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of IL17B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.