IGJ_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IGJ_MOUSE
• UniProt AC: P01592
• Protein Name: Immunoglobulin J chain {ECO:0000312|MGI:MGI:96493}
• Gene Name: Jchain {ECO:0000312|MGI:MGI:96493}
• Organism: Mus musculus (Mouse).
• Sequence Length: 159
• Subcellular Localization: Secreted .
• Protein Description: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component..
• Protein Sequence: MKTHLLLWGVLAIFVKAVLVTGDDEATILADNKCMCTRVTSRIIPSTEDPNEDIVERNIRIVVPLNNRENISDPTSPLRRNFVYHLSDVCKKCDPVEVELEDQVVTATQSNICNEDDGVPETCYMYDRNKCYTTMVPLRYHGETKMVQAALTPDSCYPD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	N-linked_Glycosylation	VPLNNRENISDPTSP EECCCCCCCCCCCCH	35.51	-
92	Ubiquitination	HLSDVCKKCDPVEVE HHHHHHHHCCCEEEE	38.45	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IGJ_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IGJ_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IGJ_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of IGJ_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.