| UniProt ID | IGF2_MOUSE | |
|---|---|---|
| UniProt AC | P09535 | |
| Protein Name | Insulin-like growth factor II | |
| Gene Name | Igf2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 180 | |
| Subcellular Localization | Secreted . | |
| Protein Description | The insulin-like growth factors possess growth-promoting activity (Probable). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development (Probable). [PubMed: 2330056] | |
| Protein Sequence | MGIPVGKSMLVLLISLAFALCCIAAYGPGETLCGGELVDTLQFVCSDRGFYFSRPSSRANRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTSQAVLPDDFPRYPVGKFFQYDTWRQSAGRLRRGLPALLRARRGRMLAKELKEFREAKRHRPLIVLPPKDPAHGGASSEMSSNHQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MGIPVGKSMLV ----CCCCCCHHHHH | 24.07 | - | |
| 4 | Phosphorylation | ----MGIPVGKSMLV ----CCCCCCHHHHH | 24.07 | - | |
| 4 (in isoform 2) | Phosphorylation | - | 24.07 | - | |
| 74 | Phosphorylation | VEECCFRSCDLALLE HHHHHHCCCCHHHHH | 7.54 | 24759943 | |
| 95 | Phosphorylation | AKSERDVSTSQAVLP CCCCCCCCCCCCCCC | 26.99 | 24899341 | |
| 96 | Phosphorylation | KSERDVSTSQAVLPD CCCCCCCCCCCCCCC | 25.38 | 24899341 | |
| 97 | Phosphorylation | SERDVSTSQAVLPDD CCCCCCCCCCCCCCC | 14.50 | 24759943 | |
| 172 | Phosphorylation | DPAHGGASSEMSSNH CCCCCCCCCCCCCCC | 30.06 | 24899341 | |
| 173 | Phosphorylation | PAHGGASSEMSSNHQ CCCCCCCCCCCCCCC | 36.46 | 24899341 | |
| 176 | Phosphorylation | GGASSEMSSNHQ--- CCCCCCCCCCCC--- | 24.76 | 24759943 | |
| 177 | Phosphorylation | GASSEMSSNHQ---- CCCCCCCCCCC---- | 36.70 | 24899341 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of IGF2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of IGF2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of IGF2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of IGF2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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