IGDC4_HUMAN - dbPTM
IGDC4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IGDC4_HUMAN
UniProt AC Q8TDY8
Protein Name Immunoglobulin superfamily DCC subclass member 4
Gene Name IGDCC4
Organism Homo sapiens (Human).
Sequence Length 1250
Subcellular Localization Cell membrane
Single-pass type I membrane protein .
Protein Description
Protein Sequence MARGDAGRGRGLLALTFCLLAARGELLLPQETTVELSCGVGPLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQAKMESLVVSWQPPPHPTQISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQEKLSDSLDMHSVTGIIVGVCLGLLCLLACMCAGLRRSPHRESLPGLSSTATPGNPALYSRARLGPPSPPAAHELESLVHPHPQDWSPPPSDVEDRAEVHSLMGGGVSEGRSHSKRKISWAQPSGLSWAGSWAGCELPQAGPRPALTRALLPPAGTGQTLLLQALVYDAIKGNGRKKSPPACRNQVEAEVIVHSDFSASNGNPDLHLQDLEPEDPLPPEAPDLISGVGDPGQGAAWLDRELGGCELAAPGPDRLTCLPEAASASCSYPDLQPGEVLEETPGDSCQLKSPCPLGASPGLPRSPVSSSA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8 (in isoform 2)Phosphorylation-33.1023927012
11 (in isoform 2)Phosphorylation-28.0623927012
13 (in isoform 2)Phosphorylation-4.0123927012
90N-linked_GlycosylationDHLHLLPNGSLWLSQ
CEEEECCCCCEEECC		53.29UniProtKB CARBOHYD
102N-linked_GlycosylationLSQPLAPNGSDESVP
ECCCCCCCCCCCCCC		57.92UniProtKB CARBOHYD
157N-linked_GlycosylationESQTVEENGTARFEC
CCCCCCCCCCEEEEE		39.34UniProtKB CARBOHYD
215PhosphorylationGPYRCVATNSARQHF
CCEEEEECCCHHHHC		14.87-
252N-linked_GlycosylationVIVAAPENTTVVSGQ
EEEECCCCCEEECCC		39.74UniProtKB CARBOHYD
286PhosphorylationRQDGKPISTDVIVLG
CCCCCCCCCCEEEEC		27.3830257219
287PhosphorylationQDGKPISTDVIVLGR
CCCCCCCCCEEEECC		34.7030257219
350PhosphorylationALSRTRASTARFVCR
HHHCCCHHHCHHHHH		21.2224719451
499PhosphorylationDLEPNTDYEFYVVAY
CCCCCCCCEEEEEEE		13.1030576142
502PhosphorylationPNTDYEFYVVAYSQL
CCCCCEEEEEEEHHH		5.1030576142
582N-linked_GlycosylationFSTEVRGNETQLMLN
EEEEECCCCCEEEHH		38.28UniProtKB CARBOHYD
584PhosphorylationTEVRGNETQLMLNSL
EEECCCCCEEEHHHC		30.8829978859
590PhosphorylationETQLMLNSLQPNKVY
CCEEEHHHCCCCCEE		25.1529978859
597PhosphorylationSLQPNKVYRVRISAG
HCCCCCEEEEEEECC		12.6624043423
602PhosphorylationKVYRVRISAGTAAGF
CEEEEEEECCCCCCC		15.3028348404
605PhosphorylationRVRISAGTAAGFGAP
EEEEECCCCCCCCCC		17.0428348404
727PhosphorylationFNKHEDGYAAVWKGK
EECCCCCEEEEEECC		12.0530576142
735PhosphorylationAAVWKGKTEKAPAPD
EEEEECCCCCCCCCC		51.9230576142
841PhosphorylationFGSVVERSTLPDRPS
CCCEEECCCCCCCCC		22.3122617229
842PhosphorylationGSVVERSTLPDRPST
CCEEECCCCCCCCCC		48.8322617229
848PhosphorylationSTLPDRPSTPPSDLR
CCCCCCCCCCCCCCC		55.2122617229
935PhosphorylationEVGPGPFSRLQDVIT
CCCCCCCHHHHHHHH		34.90-
948PhosphorylationITLQEKLSDSLDMHS
HHHHHHHCCCCCHHH		35.9022210691
950PhosphorylationLQEKLSDSLDMHSVT
HHHHHCCCCCHHHHH		23.9322210691
955PhosphorylationSDSLDMHSVTGIIVG
CCCCCHHHHHHHHHH		18.1022210691
986PhosphorylationRRSPHRESLPGLSST
CCCCCCCCCCCCCCC		39.5618669648
995PhosphorylationPGLSSTATPGNPALY
CCCCCCCCCCCHHHH		31.6410997877
1003PhosphorylationPGNPALYSRARLGPP
CCCHHHHCCCCCCCC		21.9518669648
1011PhosphorylationRARLGPPSPPAAHEL
CCCCCCCCCCCHHHH		46.8032142685
1020PhosphorylationPAAHELESLVHPHPQ
CCHHHHHHHCCCCCC		48.6026471730
1099PhosphorylationALLPPAGTGQTLLLQ
HHCCCCCCCHHHHHH		28.37-
1198PhosphorylationAPGPDRLTCLPEAAS
CCCCCCEECCHHHHH		16.94-
1238PhosphorylationSPCPLGASPGLPRSP
CCCCCCCCCCCCCCC		20.0830266825
1244PhosphorylationASPGLPRSPVSSSA-
CCCCCCCCCCCCCC-		27.9332142685
1247PhosphorylationGLPRSPVSSSA----
CCCCCCCCCCC----		23.2023312004
1248PhosphorylationLPRSPVSSSA-----
CCCCCCCCCC-----		30.4423312004
1249PhosphorylationPRSPVSSSA------
CCCCCCCCC------		30.4123312004
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IGDC4_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IGDC4_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IGDC4_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of IGDC4_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IGDC4_HUMAN

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Related Literatures of Post-Translational Modification

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