IFT88_MOUSE - dbPTM
IFT88_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IFT88_MOUSE
UniProt AC Q61371
Protein Name Intraflagellar transport protein 88 homolog
Gene Name Ift88
Organism Mus musculus (Mouse).
Sequence Length 824
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Cell projection, cilium .
Protein Description Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment..
Protein Sequence MENVHLAPETDEDDLYSGFNDYNPAYDTEELENDTGFQQAVRTSHGRRPPVTAKIPSTAVSRPIATGYGSKTSLTSSMGRPMTGTIQDGVARPMTAVRAAGFSKAALRGSAFDPLGQSRGPAPPLEAKNEDSPEEKIRQLEKKVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTSPENINLDLTYSVLFNLASQYSANEMYAEALNTYQVIVKNKMFSNAGRLKVNMGNIYLKQRNYSKAIKFYRMALDQIPSVHKEMRIKIMQNIGITFIKTGQYSDAINSFEHIMSMAPSLKAGFNLILSCFAIGDREKMKKAFQKLIAVPLEIDEDDKYISPSDDPHTNLLIEAIKNDHLRQMERERKAMAEKYIMTAAKLIAPVIEASFAVGYNWCVEVVKASQYVELANDLEINKAITYLRQKDFNQAVDTLKMFEKKDSRVKSAAATNLSFLYYLENEFAQASSYADLAVNSDRYNPSALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYKKLNRLDEALDSFLKLHAILRNSAQVLCQIANIYELMEDPNQAIEWLMQLISVVPTDSQALSKLGELYDSEGDKSQAFQYYYESYRYFPSNIEVIEWLGAYYIDTQFCEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKEIHRKFPENVECLRFLVRLCTDIGLKEVQEYATKLKRLEKMKEMREQRIKSGRDSSGGSRSKREGSAGSDSGQNNSASSKSERLSAKLRALPGTDEPYESSGNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
58PhosphorylationVTAKIPSTAVSRPIA
CCCCCCCCCCCCCCC
26.2329514104
66PhosphorylationAVSRPIATGYGSKTS
CCCCCCCCCCCCCCC
31.4929514104
443AcetylationDTLKMFEKKDSRVKS
HHHHHHHHCCHHHHH
51.0923864654
490UbiquitinationNPSALTNKGNTVFAN
CHHHHCCCCCEEEEC
48.58-
515PhosphorylationKEALRNDSSCTEALY
HHHHHCCCHHHHHHH
30.75-
744PhosphorylationSRSKREGSAGSDSGQ
CCCCCCCCCCCCCCC
25.3823684622
749PhosphorylationEGSAGSDSGQNNSAS
CCCCCCCCCCCCCCC
43.93-
756PhosphorylationSGQNNSASSKSERLS
CCCCCCCCCHHHHHH
37.81-
757PhosphorylationGQNNSASSKSERLSA
CCCCCCCCHHHHHHH
39.66-
801PhosphorylationPQIERPKTAAKKRID
CCCCCCCCHHHHCCC
34.2325338131
805AcetylationRPKTAAKKRIDEDDF
CCCCHHHHCCCCCCC
50.2722902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IFT88_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IFT88_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IFT88_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of IFT88_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IFT88_MOUSE

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Related Literatures of Post-Translational Modification

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